Anxiety over GABA(A) receptor structure relieved by AChBP.
about
A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sitesThe benzodiazepine binding site of GABA A receptors as a target for the development of novel anxiolyticsProton modulation of recombinant GABA(A) receptors: influence of GABA concentration and the beta subunit TM2-TM3 domainGABA A receptors: subtypes provide diversity of function and pharmacologyInternational Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. UpdateInvestigation of gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibilityEditing modifies the GABA(A) receptor subunit alpha3Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELICPrinciples of agonist recognition in Cys-loop receptorsMolecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoniMarine Toxins Targeting Ion ChannelsIdentification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513.Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.The dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites.Extracellular domain nicotinic acetylcholine receptors formed by alpha4 and beta2 subunits.A virtual screening study of the acetylcholine binding protein using a relaxed-complex approachAn epilepsy-related region in the GABA(A) receptor mediates long-distance effects on GABA and benzodiazepine binding sites.Expression of GABAergic receptors in mouse taste receptor cellsA residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor.New insights into the GABA(A) receptor structure and orthosteric ligand binding: receptor modeling guided by experimental data.Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domainPhotochemical proteolysis of an unstructured linker of the GABAAR extracellular domain prevents GABA but not pentobarbital activation.Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity.Homology model of the GABAA receptor examined using Brownian dynamicsDesign, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models.Four amino acids in the alpha subunits determine the gamma-aminobutyric acid sensitivities of GABAA receptor subtypes.SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat α3, α5, or α6 subunit subtypes coexpressed with β3 and γ2 subunits.Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy.Ligand- and subunit-specific conformational changes in the ligand-binding domain and the TM2-TM3 linker of {alpha}1 {beta}2 {gamma}2 GABAA receptorsCrystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.γ-Aminobutyric acid (GABA) signalling in plants.A state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor.Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexesA tight coupling between β₂Y97 and β₂F200 of the GABA(A) receptor mediates GABA bindingDiscrete M3-M4 intracellular loop subdomains control specific aspects of γ-aminobutyric acid type A receptor function.The TM2 6' position of GABA(A) receptors mediates alcohol inhibitionModulating inhibitory ligand-gated ion channels.Glycine receptors: recent insights into their structural organization and functional diversity.Improved surface modification approach for micromechanical biosensors.
P2860
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P2860
Anxiety over GABA(A) receptor structure relieved by AChBP.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Anxiety over GABA
@nl
Anxiety over GABA(A) receptor structure relieved by AChBP.
@ast
Anxiety over GABA(A) receptor structure relieved by AChBP.
@en
type
label
Anxiety over GABA
@nl
Anxiety over GABA(A) receptor structure relieved by AChBP.
@ast
Anxiety over GABA(A) receptor structure relieved by AChBP.
@en
prefLabel
Anxiety over GABA
@nl
Anxiety over GABA(A) receptor structure relieved by AChBP.
@ast
Anxiety over GABA(A) receptor structure relieved by AChBP.
@en
P50
P1476
Anxiety over GABA(A) receptor structure relieved by AChBP.
@en
P304
P356
10.1016/S0968-0004(02)02092-3
P577
2002-06-01T00:00:00Z