Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
about
Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19KBAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic grooveHeterodimerization of BAK and MCL-1 activated by detergent micellesThe permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosisLoss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisThe procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulumCaspases: pharmacological manipulation of cell deathKaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosisHexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanismCaspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosolImmortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of BaxMetabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implicationThe role of BH3-mimetic drugs in the treatment of pediatric hepatoblastomaMarine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)Humanin binds and nullifies Bid activity by blocking its activation of Bax and BakUncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondriaDeath-associated protein-3, DAP-3, correlates with preoperative chemotherapy effectiveness and prognosis of gastric cancer patients following perioperative chemotherapy and radical gastrectomy.Propagation of the apoptotic signal by mitochondrial wavesDoes antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3The Effect of Growth Hormone Administration on the Regulation of Mitochondrial Apoptosis in-VivoBCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerUp-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replicationSpatial and temporal changes in Bax subcellular localization during anoikisBax and Bak independently promote cytochrome C release from mitochondriaEthanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brainEvaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c releaseCalcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosisRegulation of the cell cycle and apoptosis by the oncogenes of adenovirusMolecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma.Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases.Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activationPaclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells.Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila.Facilitation of mitochondrial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein.Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathwaySpontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1Emerging Bcl-2 inhibitors for the treatment of cancer.Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance
P2860
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P2860
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@ast
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@en
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@nl
type
label
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@ast
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@en
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@nl
prefLabel
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@ast
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@en
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@nl
P2093
P356
P1476
Pro-apoptotic cascade activate ...... n the release of cytochrome c.
@en
P2093
P2888
P304
P356
10.1038/SJ.CDD.4400783
P577
2000-12-01T00:00:00Z