A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
about
Comparative genomic analysis of three Leishmania species that cause diverse human diseasePhenotypic analysis of trypanothione synthetase knockdown in the African trypanosomeDissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methodsLeishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activitiesChemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasisEvasion of the Immune Response by Trypanosoma cruzi during Acute InfectionProtein S-Thiolation by Glutathionylspermidine (Gsp): THE ROLE OF ESCHERICHIA COLI Gsp SYNTHETASE/AMIDASE IN REDOX REGULATIONMolecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetaseStage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovaniIdentification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic TrypanosomatidsPolyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilitiesKinetics and redox-sensitive oligomerisation reveal negative subunit cooperativity in tryparedoxin peroxidase of Trypanosoma brucei brucei.Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.Transcriptome of Aphanomyces euteiches: new oomycete putative pathogenicity factors and metabolic pathwaysBiosynthesis of trypanothione in Trypanosoma brucei brucei.Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulatorThe parasite-specific trypanothione metabolism of trypanosoma and leishmania.Trypanothione synthesis in crithidia revisited.Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase.Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease.Leishmania antimony resistance: what we know what we can learn from the field.Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi.Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015).Transgenic biosynthesis of trypanothione protects Escherichia coli from radiation-induced toxicity.Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modelingATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.Properties of phosphoenolpyruvate mutase, the first enzyme in the aminoethylphosphonate biosynthetic pathway in Trypanosoma cruzi.Cloning, expression, characterization and inhibition studies on trypanothione synthetase, a drug target enzyme, from Leishmania donovani.A novel polyamine acyltransferase responsible for the accumulation of spermidine conjugates in Arabidopsis seed.Biochemistry and Physiology of Reactive Oxygen Species in Euglena.Skl, a novel choline-binding N-acetylmuramoyl-L-alanine amidase of Streptococcus mitis SK137 containing a CHAP domain.Drug target validation of the trypanothione pathway enzymes through metabolic modelling.The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione
P2860
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P2860
A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@ast
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@en
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@nl
type
label
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@ast
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@en
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@nl
prefLabel
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@ast
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@en
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@nl
P2093
P2860
P356
P1476
A single enzyme catalyses form ...... ermidine in Trypanosoma cruzi.
@en
P2093
Emmanuel Tetaud
Mark R Ariyanayagam
Stephanie S Warnon
P2860
P304
35853-35861
P356
10.1074/JBC.M204403200
P407
P577
2002-07-16T00:00:00Z