Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant.
about
Structure of the human lung cytochrome P450 2A13Genetic polymorphisms of CYP2A13 and its relationship to nasopharyngeal carcinoma in the Cantonese populationCharacterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokersStructural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Contributions of human enzymes in carcinogen metabolismMechanisms of differential expression of the CYP2A13 7520C and 7520G alleles in human lung: allelic expression analysis for CYP2A13 heterogeneous nuclear RNA, and evidence for the involvement of multiple cis-regulatory single nucleotide polymorphismConversion events in gene clustersCYP2A13 genetic polymorphism in French Caucasian, Gabonese and Tunisian populations.A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.Suppression of pulmonary CYP2A13 expression by carcinogen-induced lung tumorigenesis in a CYP2A13-humanized mouse model.Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.Genetic susceptibility to tobacco-related cancer.Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse modelThe pneumotoxin 3-methylindole is a substrate and a mechanism-based inactivator of CYP2A13, a human cytochrome P450 enzyme preferentially expressed in the respiratory tract.Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.Benzylmorpholine analogs as selective inhibitors of lung cytochrome P450 2A13 for the chemoprevention of lung cancer in tobacco users.Molecular modelling of CYP2A enzymes: application to metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.
P2860
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P2860
Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@ast
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@en
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@nl
type
label
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@ast
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@en
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@nl
prefLabel
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@ast
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@en
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@nl
P2093
P356
P1476
Genetic polymorphisms of the h ...... ation of an Arg257Cys variant.
@en
P2093
Hongming Li
Michele Caggana
Qing-Yu Zhang
Xinxin Ding
Xiuling Zhang
P304
P356
10.1124/JPET.302.2.416
P407
P577
2002-08-01T00:00:00Z