Defining and combating the mechanisms of triclosan resistance in clinical isolates of Staphylococcus aureus.
about
Mode of Action, In Vitro Activity, and In Vivo Efficacy of AFN-1252, a Selective Antistaphylococcal FabI InhibitorRational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase InhibitorResistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) AntibioticsMethicillin-resistant Staphylococcus aureus: an evolutionary, epidemiologic, and therapeutic odysseyTriclosan: current status, occurrence, environmental risks and bioaccumulation potentialMechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureusN-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.Investigational antimicrobial agents of 2013.Staphylococcus epidermidis isolated in 1965 are more susceptible to triclosan than current isolates.Staphylococcus aureus but not Listeria monocytogenes adapt to triclosan and adaptation correlates with increased fabI expression and agr deficiencyPotential impact of increased use of biocides in consumer products on prevalence of antibiotic resistanceThe impact of triclosan on the spread of antibiotic resistance in the environment.A very early-branching Staphylococcus aureus lineage lacking the carotenoid pigment staphyloxanthinMutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression.Fatty acid biosynthesis as a target for novel antibacterialsCharacterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonellaAqueous Molecular Dynamics Simulations of the M. tuberculosis Enoyl-ACP Reductase-NADH System and Its Complex with a Substrate Mimic or Diphenyl Ethers Inhibitors.Identification and characterization of TriABC-OpmH, a triclosan efflux pump of Pseudomonas aeruginosa requiring two membrane fusion proteinsReduced triclosan susceptibility in methicillin-resistant Staphylococcus epidermidis.Resistance to AFN-1252 arises from missense mutations in Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI).Triclosan - an update.Drug repurposing screens and synergistic drug-combinations for infectious diseases.Exogenous fatty acid metabolism in bacteria.Clinical Relevance of Type II Fatty Acid Synthesis Bypass in Staphylococcus aureus.Antibacterial activity of four mouthrinses containing triclosan against salivary Staphylococcus aureus.Occurrence, efficacy, metabolism, and toxicity of triclosan.Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification.Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.Triclosan resistance in Salmonella enterica serovar Typhimurium.Distribution of triclosan-resistant genes in major pathogenic microorganisms revealed by metagenome and genome-wide analysis.No evidence of triclosan-resistant bacteria following long-term use of triclosan-containing toothpaste.Staphylococcus aureus utilizes host-derived lipoprotein particles as sources of exogenous fatty acids.
P2860
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P2860
Defining and combating the mechanisms of triclosan resistance in clinical isolates of Staphylococcus aureus.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Defining and combating the mec ...... ates of Staphylococcus aureus.
@ast
Defining and combating the mec ...... ates of Staphylococcus aureus.
@en
Defining and combating the mec ...... ates of Staphylococcus aureus.
@nl
type
label
Defining and combating the mec ...... ates of Staphylococcus aureus.
@ast
Defining and combating the mec ...... ates of Staphylococcus aureus.
@en
Defining and combating the mec ...... ates of Staphylococcus aureus.
@nl
prefLabel
Defining and combating the mec ...... ates of Staphylococcus aureus.
@ast
Defining and combating the mec ...... ates of Staphylococcus aureus.
@en
Defining and combating the mec ...... ates of Staphylococcus aureus.
@nl
P2093
P2860
P1476
Defining and combating the mec ...... ates of Staphylococcus aureus.
@en
P2093
Dalia R Jakas
Damien McDevitt
David J Payne
Jianzhong Huang
Kenneth A Newlander
Mark A Seefeld
Martha S Head
Nicola G Wallis
P2860
P304
P356
10.1128/AAC.46.11.3343-3347.2002
P407
P577
2002-11-01T00:00:00Z