Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys.
about
Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activationKappa opioid antagonists: past successes and future prospectsFlavonoids as opioid receptor ligands: identification and preliminary structure-activity relationshipsKappa-opioid ligands in the study and treatment of mood disordersLong-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinaseEffectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-inducedLong-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicitySelective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters.Activation of the opioid μ1, but not δ or κ, receptors is required for nicotine reinforcement in a rat model of drug self-administration.Major Depressive Disorder and Kappa Opioid Receptor Antagonists.The effects of morphine, naloxone, and κ opioid manipulation on endocrine functioning and social behavior in monogamous titi monkeys (Callicebus cupreus).Early role of the κ opioid receptor in ethanol-induced reinforcementAnalgesic Efficacy of Firocoxib, a Selective Inhibitor of Cyclooxygenase 2, in a Mouse Model of Incisional Pain.Effects of butorphanol on morphine-induced itch and analgesia in primates.Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.Development of κ opioid receptor antagonists.Kinase cascades and ligand-directed signaling at the kappa opioid receptor.Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.Management of chronic pain in the elderly: focus on transdermal buprenorphine.Investigational drugs under development for the treatment of PTSD.Investigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice.Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor.Effect of GNTI, a kappa opioid receptor antagonist, on MK-801-induced hyperlocomotion and stereotypy in mice.Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist.Effects of local and spinal administrations of mu-opioids on postoperative pain in aged versus adult mice.Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl).Cardiorenal Effects of Kappa Opioid Peptides During Ontogeny.
P2860
Q24634808-921D4D62-EA73-4B1C-8990-0D5E211D79B5Q24647830-251FE363-7CC7-451B-B3D9-CB1332C58D4EQ24655806-5003D163-E661-43FC-A0D8-1E4687B5118AQ24657982-A29EC607-E479-4956-8E88-55582832D36DQ24685243-10073B5D-2EE7-4B98-93D2-A57F48CADFF4Q33861304-ACF0BD8B-F9E9-47C1-8778-BEA3C376B4B5Q34285100-3965F3DC-3EED-4BE1-BD0C-159F8CEF43A6Q34366661-0884482D-CDA9-41E3-A34B-6D3EEBFCC851Q34482188-FD37BE9E-9703-4416-ABF5-5C76EB3D73EEQ34527874-4ADEE641-FCE6-43BC-A928-7CDC4D2483FCQ35034396-BCCD63CF-67C8-4882-99A1-44690AD595DFQ35788833-B7EDA1FE-451A-412A-BFC2-E502F7817E0EQ35906890-DF868CD5-8228-4C86-97B9-57AC16083EECQ36008808-7672E9F2-A622-4F70-876E-F2D75D9C3B97Q36138467-AFA992E1-DA2B-45F7-B4C4-732FCDA55F43Q36728154-0F177B62-BF22-466D-B747-BACE5CB592ACQ36900733-4D906B33-C5E1-4C62-965B-82CFE3DF0340Q37091288-B3D7E783-3E05-49F1-9062-A527609EEEFAQ37316802-BA158F7C-5708-446A-A9F0-3116D18F14EAQ38378939-E515BDFD-9044-496C-A6AD-5B50E12AA313Q38901893-AEC1375C-EA3D-4756-A5D5-0B3D1EC48D82Q41639865-84E03F96-BB8E-4CEF-861C-F0DA24F53790Q41872689-22D0525B-5D9B-489F-B393-720788DCA442Q44332455-B6C35813-BE32-4477-9F38-B56BE7FDF790Q44348482-F8145E11-56A6-43BC-A746-F8DB45342C16Q47154586-3EE15AC8-0F97-492E-96A0-800A00C5FE0AQ49608912-3B406C27-9160-4987-BEAD-34D5901FAEC3Q55564405-E3D88901-423C-41F1-8FB1-850961555B58
P2860
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@ast
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@en
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole
@nl
type
label
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@ast
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@en
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole
@nl
prefLabel
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@ast
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@en
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole
@nl
P2093
P1433
P1476
Kappa opioid antagonist effect ...... ed behavior in rhesus monkeys.
@en
P2093
David C Linsenmayer
Nancy K Mello
Philip S Portoghese
S Stevens Negus
P2888
P304
P356
10.1007/S00213-002-1038-X
P577
2002-03-13T00:00:00Z
P6179
1039595792