Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation
about
Cullin family proteins and tumorigenesis: genetic association and molecular mechanismsIgH chain class switch recombination: mechanism and regulationDifferential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutationProximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Refining the Neuberger model: Uracil processing by activated B cells.Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development.Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.Mutagenesis by AID: Being in the Right Place at the Right Time.AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerasesUNG protects B cells from AID-induced telomere loss.The dual nature of mismatch repair as antimutator and mutator: for better or for worse.MBD4 Facilitates Immunoglobulin Class Switch Recombination.Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers.Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.Molecular Methods and Bioinformatic Tools for Adjuvant Characterization by High-Throughput Sequencing.SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.
P2860
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P2860
Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
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name
Uracil excision by endogenous ...... utions during somatic mutation
@ast
Uracil excision by endogenous ...... utions during somatic mutation
@en
Uracil excision by endogenous ...... utions during somatic mutation
@nl
type
label
Uracil excision by endogenous ...... utions during somatic mutation
@ast
Uracil excision by endogenous ...... utions during somatic mutation
@en
Uracil excision by endogenous ...... utions during somatic mutation
@nl
prefLabel
Uracil excision by endogenous ...... utions during somatic mutation
@ast
Uracil excision by endogenous ...... utions during somatic mutation
@en
Uracil excision by endogenous ...... utions during somatic mutation
@nl
P2093
P2860
P356
P1476
Uracil excision by endogenous ...... utions during somatic mutation
@en
P2093
Cristina Rada
Felix A Dingler
Kristin Kemmerich
Michael S Neuberger
P2860
P304
P356
10.1002/EJI.201444482
P407
P577
2014-05-27T00:00:00Z