Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility. - Wikidata - wikimedia - TriplyDB

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.

http://www.wikidata.org/entity/Q34155960

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Modifications of histone cores and tails in V(D)J recombination B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5 E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene Elucidation of IgH intronic enhancer functions via germ-line deletion Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.Gene segment selection in V(D)J recombination: accessibility and beyond.The center of accessibility: Dβ control of V(D)J recombination T cell receptor (TCR) alpha/delta locus enhancer identity and position are critical for the assembly of TCR delta and alpha variable region genes.Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element.Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.Regulating antigen-receptor gene assembly.Discrete functional elements required for initiation activity of the Chinese hamster dihydrofolate reductase origin beta at ectopic chromosomal sites.DNA double-strand breaks relieve USF-mediated repression of Dβ2 germline transcription in developing thymocytes.Many levels of control of V gene rearrangement frequency.How to keep V(D)J recombination under control.Regulation of immunoglobulin heavy-chain gene rearrangements.Monoallelic gene expression: a repertoire of recurrent themes.Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus.Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments.Influence of a CTCF-Dependent Insulator on Multiple Aspects of Enhancer-Mediated Chromatin Organization Histone reader BRWD1 targets and restricts recombination to the Igk locus.Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription.Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4.A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling.Turning T-cell receptor beta recombination on and off: more questions than answers.Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters.Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes Expression of T-cell receptor genes during early T-cell development.A streamlined method for rapid and sensitive chromatin immunoprecipitation.Promoter activity 5' of Dbeta2 is coordinated by E47, Runx1, and GATA-3.Allelic exclusion of immunoglobulin genes: models and mechanisms.Epigenetic regulation of V(D)J recombination.Regulation of antigen receptor gene assembly by genetic-epigenetic crosstalk.The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination.Germline transcription of multiple TCR-Vbeta genes in cloned T-cell lines.Targeted inhibition of V(D)J recombination by a histone methyltransferase.The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion.

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P2860

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.

http://www.wikidata.org/entity/Q34155960

description

2002 nî lūn-bûn

@nan

2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի օգոստոսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Regulation of V(D)J recombinat ...... in gene segment accessibility.

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Regulation of V(D)J recombinat ...... in gene segment accessibility.

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type

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Regulation of V(D)J recombinat ...... in gene segment accessibility.

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Regulation of V(D)J recombinat ...... in gene segment accessibility.

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Regulation of V(D)J recombinat ...... in gene segment accessibility.

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Regulation of V(D)J recombinat ...... in gene segment accessibility.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Regulation of V(D)J recombinat ...... in gene segment accessibility.

@en

P2093

Amber Meade

http://www.w3.org/2001/XMLSchema#string

Eugene M Oltz

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Michael L Sikes

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Michael S Krangel

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Rajkamal Tripathi

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P2860

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

Histone acetylation and transcriptional regulatory mechanisms

Alteration of nucleosome structure as a mechanism of transcriptional regulation

V(D)J recombination: on the cutting edge.

Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate

Unequal access: regulating V(D)J recombination through chromatin remodeling.

A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice

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12309-12314

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scholarly article

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10.1073/PNAS.182166699

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19

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99

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11190959

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12196630

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129441

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