Allelic exclusion of immunoglobulin genes: models and mechanisms.
about
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2Long-Range Regulation of V(D)J RecombinationStochastic gene expression in mammals: lessons from olfactionHeterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and RepairIndependent recruitment of Igh alleles in V(D)J recombination.Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis.Clonally stable Vκ allelic choice instructs Igκ repertoire.Using next-generation RNA sequencing to identify imprinted genes.The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusionFunctional interrogation of an odorant receptor locus reveals multiple axes of transcriptional regulation.A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.Insertion of an imprinted insulator into the IgH locus reveals developmentally regulated, transcription-dependent control of V(D)J recombination.Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production.The multiple shark Ig H chain genes rearrange and hypermutate autonomously.Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus.Allele-specific gene expression and epigenetic modifications and their application to understanding inheritance and cancer.Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice.Assessment of antibody library diversity through next generation sequencing and technical error compensation.Non-CG Methylation in the Human Genome.The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangementsRole of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition.Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2.Generation of Monoclonal Antibodies against Immunoglobulin Proteins of the Domestic Ferret (Mustela putorius furo).Design principles of adaptive immune systems.Genetic variations in multiple myeloma I: effect on risk of multiple myeloma.Acute lymphoblastic leukemia and developmental biology: a crucial interrelationshipMechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Characterization of a new V gene replacement in the absence of activation-induced cytidine deaminase and its contribution to human B-cell receptor diversity.V(D)J Recombination Exploits DNA Damage Responses to Promote Immunity.The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(-/-) mice.Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells.Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in BeninThe emerging landscape of in vitro and in vivo epigenetic allelic effects.
P2860
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P2860
Allelic exclusion of immunoglobulin genes: models and mechanisms.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@en
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@nl
type
label
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@en
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@nl
prefLabel
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@en
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@nl
P2860
P1476
Allelic exclusion of immunoglobulin genes: models and mechanisms.
@en
P2093
Christian Vettermann
Mark S Schlissel
P2860
P356
10.1111/J.1600-065X.2010.00935.X
P577
2010-09-01T00:00:00Z