Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
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Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityAcetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediatesStimulation of flap endonuclease-1 by the Bloom's syndrome proteinHuman DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediatesIsolation of human Dna2 endonuclease and characterization of its enzymatic propertiesBiochemical analysis of human Dna2Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replicationIdling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replicationComponents of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processingAn alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicaseEnzymatic properties of the Caenorhabditis elegans Dna2 endonuclease/helicase and a species-specific interaction between RPA and Dna2In vivo and in vitro studies of Mgs1 suggest a link between genome instability and Okazaki fragment processing.A network of multi-tasking proteins at the DNA replication fork preserves genome stabilityThe RFC clamp loader: structure and functionDNA polymerase delta in DNA replication and genome maintenanceThe C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligaseCrystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substratesThe Structure of the Mammalian RNase H2 Complex Provides Insight into RNA{middle dot}DNA Hybrid Processing to Prevent Immune DysfunctionStructure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation.RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.Elg1 forms an alternative RFC complex important for DNA replication and genome integrityThe MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing.The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domainsDna2 exhibits a unique strand end-dependent helicase function.Involvement of Vts1, a structure-specific RNA-binding protein, in Okazaki fragment processing in yeast.Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.Single strand annealing and ATP-independent strand exchange activities of yeast and human DNA2: possible role in Okazaki fragment maturation.Reconstituted Okazaki fragment processing indicates two pathways of primer removal.Evidence for a role of FEN1 in maintaining mitochondrial DNA integrityDna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nickGenetic instability in budding and fission yeast-sources and mechanismsA novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phaseAn extended network of genomic maintenance in the archaeon Pyrococcus abyssi highlights unexpected associations between eucaryotic homologsA general approach to break the concentration barrier in single-molecule imaging.Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro.Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiaeThe protein components and mechanism of eukaryotic Okazaki fragment maturation.On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing.
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Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
description
2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@ast
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@en
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@nl
type
label
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@ast
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@en
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@nl
prefLabel
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@ast
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@en
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@nl
P2093
P2860
P356
P1476
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.
@en
P2093
Dmitry A Gordenin
Peter M J Burgers
Rao Ayyagari
Xavier V Gomes
P2860
P304
P356
10.1074/JBC.M209801200
P407
P577
2002-11-06T00:00:00Z