Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells
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Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cellsAn old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 Å supports a novel mechanism for its anticancer and antiproliferative effectsMicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancersCaffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathwaysEpidermal growth factor stimulates nuclear factor-κB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cellsSulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal modelHSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.ALDOSE REDUCTASE: New Insights for an Old Enzyme.Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders.Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cellsTargeting aldose reductase for the treatment of cancerAldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrestCyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway.4-Hydroxynonenal in the pathogenesis and progression of human diseases.Development of aldose reductase inhibitors for the treatment of inflammatory disorders.Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human CancersInhibition of aldose reductase prevents angiogenesis in vitro and in vivo.Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expressionAldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity.Aldose reductase interacts with AKT1 to augment hepatic AKT/mTOR signaling and promote hepatocarcinogenesis.Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells.Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.Unveiling differentially expressed genes upon regulation of transcription factors in sepsis.
P2860
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P2860
Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells
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2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
@zh-hk
2010年論文
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2010年論文
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2010年论文
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name
Inhibition of aldose reductase ...... ay in human colon cancer cells
@ast
Inhibition of aldose reductase ...... ay in human colon cancer cells
@en
Inhibition of aldose reductase ...... ay in human colon cancer cells
@nl
type
label
Inhibition of aldose reductase ...... ay in human colon cancer cells
@ast
Inhibition of aldose reductase ...... ay in human colon cancer cells
@en
Inhibition of aldose reductase ...... ay in human colon cancer cells
@nl
prefLabel
Inhibition of aldose reductase ...... ay in human colon cancer cells
@ast
Inhibition of aldose reductase ...... ay in human colon cancer cells
@en
Inhibition of aldose reductase ...... ay in human colon cancer cells
@nl
P2093
P2860
P1476
Inhibition of aldose reductase ...... ay in human colon cancer cells
@en
P2093
Kota V Ramana
Ravinder Tammali
Satish K Srivastava
P2860
P304
P356
10.1158/1535-7163.MCT-09-0795
P577
2010-03-30T00:00:00Z