A dominant block to HIV-1 replication at reverse transcription in simian cells
about
Involvement of Clathrin-Mediated Endocytosis in Human Immunodeficiency Virus Type 1 EntryTRIM5α and Species Tropism of HIV/SIVCHD1 and CHD2 are positive regulators of HIV-1 gene expressionTRIM family proteins: retroviral restriction and antiviral defenceCyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cellsProteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infectionSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorTrim5alpha protein restricts both HIV-1 and murine leukemia virusThe human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activitiesRetrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alphaIn defense of the cell: TRIM5alpha interception of mammalian retrovirusesLow pH is required for avian sarcoma and leukosis virus Env-dependent viral penetration into the cytosol and not for viral uncoatingHow SAMHD1 changes our view of viral restrictionIdentification of novel mutations responsible for resistance to MK-2048, a second-generation HIV-1 integrase inhibitorAll three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restrictionEarly steps of retrovirus replicative cycleIntracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.Nonhuman primate models for HIV/AIDS vaccine developmentRhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfacesFates of retroviral core components during unrestricted and TRIM5-restricted infectionLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationApparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αsGene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxinSIV replication in human cellsTRIM5 alpha cytoplasmic bodies are highly dynamic structures.Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusionRecruitment and dynamics of proteasome association with rhTRIM5α cytoplasmic complexes during HIV-1 infection.Macaques as model hosts for studies of HIV-1 infectionA specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.A SNAP-tagged derivative of HIV-1--a versatile tool to study virus-cell interactions.Identification of synthetic endothelial cell-specific promoters by use of a high-throughput screen.Proteasomal degradation of TRIM5alpha during retrovirus restrictionDemonstration of a novel HIV-1 restriction phenotype from a human T cell lineNovel approaches to inhibiting HIV-1 replication.The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage siteRetrovirus restriction by TRIM5alpha variants from Old World and New World primatesVirus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domainThe B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesSpecies-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction
P2860
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P2860
A dominant block to HIV-1 replication at reverse transcription in simian cells
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A dominant block to HIV-1 replication at reverse transcription in simian cells
@ast
A dominant block to HIV-1 replication at reverse transcription in simian cells
@en
A dominant block to HIV-1 replication at reverse transcription in simian cells
@nl
type
label
A dominant block to HIV-1 replication at reverse transcription in simian cells
@ast
A dominant block to HIV-1 replication at reverse transcription in simian cells
@en
A dominant block to HIV-1 replication at reverse transcription in simian cells
@nl
prefLabel
A dominant block to HIV-1 replication at reverse transcription in simian cells
@ast
A dominant block to HIV-1 replication at reverse transcription in simian cells
@en
A dominant block to HIV-1 replication at reverse transcription in simian cells
@nl
P2093
P2860
P356
P1476
A dominant block to HIV-1 replication at reverse transcription in simian cells
@en
P2093
Carsten Münk
Ginger Lucero
Nathaniel R Landau
Stephanie M Brandt
P2860
P304
13843-13848
P356
10.1073/PNAS.212400099
P407
P577
2002-10-04T00:00:00Z