Abrogation of Ref1 retrovirus restriction in human cells
about
TRIM5alpha selectively binds a restriction-sensitive retroviral capsidProteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infectionThe human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activitiesAll three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restrictionEarly steps of retrovirus replicative cycleGene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent mannerLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationIntrinsic antiviral immunityAbrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.Retrovirus restriction by TRIM5alpha variants from Old World and New World primatesThe B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesSpecies-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restrictionSUMO-interacting motifs of human TRIM5α are important for antiviral activityAn envelope-determined, pH-independent endocytic route of viral entry determines the susceptibility of human immunodeficiency virus type 1 (HIV-1) and HIV-2 to Lv2 restriction.Capsid processing requirements for abrogation of Fv1 and Ref1 restrictionCellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropismRestriction of lentivirus in monkeysA dominant block to HIV-1 replication at reverse transcription in simian cellsCyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cellsEvolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionRole of Human TRIM5α in Intrinsic Immunity.Control of viral infectivity by tripartite motif proteins.Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.Host restriction factors blocking retroviral replicationTRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation.The control of viral infection by tripartite motif proteins and cyclophilin A.Capsid-dependent and -independent postentry restriction of primate lentivirus tropism in rodent cellsAn invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection.Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsidPrimate and feline lentiviruses in current intrinsic immunity research: the cat is back.Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells.As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity.Characterization of murine leukemia virus restriction in mammals.Restriction of multiple divergent retroviruses by Lv1 and Ref1Retroviral restriction factors Fv1 and TRIM5alpha act independently and can compete for incoming virus before reverse transcription.
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P2860
Abrogation of Ref1 retrovirus restriction in human cells
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Abrogation of Ref1 retrovirus restriction in human cells
@ast
Abrogation of Ref1 retrovirus restriction in human cells
@en
Abrogation of Ref1 retrovirus restriction in human cells
@nl
type
label
Abrogation of Ref1 retrovirus restriction in human cells
@ast
Abrogation of Ref1 retrovirus restriction in human cells
@en
Abrogation of Ref1 retrovirus restriction in human cells
@nl
prefLabel
Abrogation of Ref1 retrovirus restriction in human cells
@ast
Abrogation of Ref1 retrovirus restriction in human cells
@en
Abrogation of Ref1 retrovirus restriction in human cells
@nl
P2860
P1433
P1476
Abrogation of Ref1 retrovirus restriction in human cells
@en
P2093
Mary Collins
Yasuhiro Takeuchi
P2860
P304
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10.1128/JVI.76.5.2548-2550.2002
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P50
P577
2002-03-01T00:00:00Z