Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function.
about
Getting 'Smad' about obesity and diabetesSmad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat dietCamurati-Engelmann disease: review of the clinical, radiological, and molecular data of 24 families and implications for diagnosis and treatmentA critical role for the Sp1-binding sites in the transforming growth factor-beta-mediated inhibition of lipoprotein lipase gene expression in macrophagesThe Role of Bone Marrow Microenvironment in Governing the Balance between Osteoblastogenesis and AdipogenesisMolecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive MoleculesRegulation of Adipocyte Differentiation via MicroRNAsThe Bone Marrow-Derived Stromal Cells: Commitment and Regulation of AdipogenesisHematopoietic stem cell-derived adipocytes and fibroblasts in the tumor microenvironmentTGF-β family signaling in stem cellsRepression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiationTGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling MechanismsBrown adipose tissue: Recent insights into development, metabolic function and therapeutic potentialLinking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.The role of paracrine and autocrine signaling in the early phase of adipogenic differentiation of adipose-derived stem cells.Lentiviral arrays for live-cell dynamic monitoring of gene and pathway activity during stem cell differentiation.Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem CellsSoluble Factors on Stage to Direct Mesenchymal Stem Cells Fate.Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis.Transcription factor Smad3 is required for the inhibition of adipogenesis by retinoic acid.Cellular bioenergetics as a target for obesity therapy.Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta.The small molecule phenamil is a modulator of adipocyte differentiation and PPARgamma expressionHypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signalingProlyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells.Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways.Expression of transforming growth factor β and its correlation with lipodystrophy in oral submucous fibrosis: an immunohistochemical studyTopological organization of multichromosomal regions by the long intergenic noncoding RNA FirreSca-1 is negatively regulated by TGF-beta1 in myogenic cells.Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype.Protection from obesity and diabetes by blockade of TGF-β/Smad3 signalingCharacterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling.Defective myofibroblast formation from mesenchymal stem cells in the aging murine heart rescue by activation of the AMPK pathway.Expression profiling and structural characterization of microRNAs in adipose tissues of hibernating ground squirrelsCCN2 requires TGF-β signalling to regulate CCAAT/enhancer binding proteins and inhibit fat cell differentiation.Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium.Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors.Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction
P2860
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P2860
Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Transforming growth factor-bet ...... /EBP transactivation function.
@ast
Transforming growth factor-bet ...... /EBP transactivation function.
@en
Transforming growth factor-bet ...... CCAAT/enhancer-binding protein
@nl
type
label
Transforming growth factor-bet ...... /EBP transactivation function.
@ast
Transforming growth factor-bet ...... /EBP transactivation function.
@en
Transforming growth factor-bet ...... CCAAT/enhancer-binding protein
@nl
prefLabel
Transforming growth factor-bet ...... /EBP transactivation function.
@ast
Transforming growth factor-bet ...... /EBP transactivation function.
@en
Transforming growth factor-bet ...... CCAAT/enhancer-binding protein
@nl
P356
P1476
Transforming growth factor-bet ...... /EBP transactivation function.
@en
P2093
Rik Derynck
P304
P356
10.1074/JBC.M212259200
P407
P577
2003-01-09T00:00:00Z