Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.
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Combination treatment including targeted therapy for advanced hepatocellular carcinomaIdentification of novel thyroid cancer-related genes and chemicals using shortest path algorithmOver-expression of Thrombospondin 4 correlates with loss of miR-142 and contributes to migration and vascular invasion of advanced hepatocellular carcinomaReceptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activationIncreased expression of MERTK is associated with a unique form of canine retinopathyMer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib.Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.MERTK as a novel therapeutic target in head and neck cancer.MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes.An intronic LINE-1 insertion in MERTK is strongly associated with retinopathy in Swedish Vallhund dogs.The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness.Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model.Antagonistic Coevolution of MER Tyrosine Kinase Expression and Function.Efferocytosis in oral squamous cell carcinoma.Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicityPD-L1 expression in bladder cancer and metastasis and its influence on oncologic outcome after cystectomyMouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis.Carcinogenesis-relevant biological events in the pathophysiology of the efferocytosis phenomenon.Efferocytosis creates a tumor microenvironment supportive of tumor survival and metastasis.Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6.
P2860
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P2860
Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.
description
2014 nî lūn-bûn
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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2014 թվականի հուլիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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Overexpression of MERTK recept ...... n a gain-of-function capacity.
@ast
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@en
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@nl
type
label
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@ast
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@en
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@nl
prefLabel
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@ast
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@en
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@nl
P2093
P2860
P356
P1476
Overexpression of MERTK recept ...... n a gain-of-function capacity.
@en
P2093
Daniel A Calarese
Khanh-Quynh N Nguyen
Raymond B Birge
Scott J Garforth
Sergei V Kotenko
Shelly Hsieh
Steve C Almo
Wen-I Tsou
P2860
P304
25737-25749
P356
10.1074/JBC.M114.570838
P407
P577
2014-07-29T00:00:00Z