Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival - Wikidata - wikimedia - TriplyDB

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

http://www.wikidata.org/entity/Q24546291

about

Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer AXL kinase as a novel target for cancer therapy The Receptor Tyrosine Kinase AXL in Cancer Progression Molecular Pathways: AXL, a Membrane Receptor Mediator of Resistance to Therapy Progress of Long Non-coding RNAs in Non-small Cell Lung Cancer Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation.Identification of proteins involved in neural progenitor cell targeting of gliomas.Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma.Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.Molecular pathways: niches in metastatic dormancy Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.Cancer secretomics reveal pathophysiological pathways in cancer molecular oncology TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34.Axl-targeted cancer imaging with humanized antibody h173.An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft.The role of epithelial plasticity in prostate cancer dissemination and treatment resistance The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma Astrocytes enhance the invasion potential of glioblastoma stem-like cells Axl as a mediator of cellular growth and survival TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus.Long non-coding RNAs in non-small cell lung cancer as biomarkers and therapeutic targets.Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation.Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells.Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib.Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors.Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.AXL is an essential factor and therapeutic target for metastatic ovarian cancer Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer

P2860

Q26823237-3BBA4067-3E51-4AE1-90C3-EEC1148A4D4B Q26863442-7C1B1375-95CC-4FCE-A1B7-8FF376D4A763 Q28068756-387FEF43-B951-4BCA-99CD-F43FE780391A Q28070028-28F8713A-A2C6-4C77-B70F-4237B7EBB4BE Q28074528-5194A6CC-61C8-4F68-B0A7-9B35618D0EFC Q28237462-86A7B2D2-7870-4276-82B2-B4C882C925F8 Q30514021-7ABE6B8B-CFA9-4453-B944-324D085C765D Q33475160-E14A4C1D-693E-4716-8C89-7B7D06F6744F Q33514834-0E75BEB0-D0E2-475E-8793-19BAEF2D6E52 Q33523409-4D864B7F-8925-4432-86DF-A7F3276CB50D Q33667156-7A1C69ED-444A-4880-9C22-14A29D05A4F9 Q33838536-68F9D75D-A21D-4E2D-A555-FEB094A5187A Q33891230-4247CB2A-1EB0-4FA8-896D-19FDC25F1F53 Q34024261-F6D07A83-3B0C-4944-8F30-D962EB1B6868 Q34077622-1D1B40F6-B5F5-49A9-AC6F-F32C7BA0C15D Q34170756-8637AA37-121C-4710-B26D-0193381F7EB2 Q34199555-2D9A7793-3C79-47D1-8F3F-6B94DE1A4849 Q34283197-194543D4-0E95-4713-A0E7-43A7B1AB0310 Q34439798-70160CBB-E9D0-431D-AA2B-4E37234C9984 Q34451033-6663C5A9-FCA0-4459-B5EB-BDC86B4FAABD Q34473426-4F33CD28-CB0E-41F0-B8E6-5BD79EDF316B Q34505037-1422F1ED-3E34-4990-B774-F00253B072C8 Q34515144-88C2AB0C-739B-4AF1-9350-5DCD4FF3BC16 Q34563444-9BD60981-F4FC-40FA-8491-63600A384B24 Q34619118-8A27F415-19A7-4136-A583-4EC11C69868F Q34794927-6EB3F886-4150-41B9-8927-00D266C3D655 Q34979215-53E6A1B2-52E8-47D1-91F1-B7894FAB172A Q34998371-1E3FE871-A367-449D-B4D0-716CB05D6254 Q35063750-9785C60D-1F21-493A-BC4C-490D5848A2F3 Q35111750-C5BAFF62-4294-40FC-88C3-32BC50CBCF5D Q35390011-440DC782-63D8-47EE-A783-E11ADE36542E Q35486521-AA06506A-3431-4E38-8039-379A382EE994 Q35674941-64BE6A73-CAFF-44C7-9F66-163AAC62CC3C Q35677075-938D62ED-8DCC-4758-9BC6-43C66D599453 Q35683415-ED9435B4-A51B-4C6B-A0A4-A20C7ED00C71 Q35832327-3D34E7F8-013D-4823-B5B8-D51D9C132E75 Q35927501-B5BD033B-B6D7-4030-AF47-C21984B98CE6 Q36044487-1A98292C-AE93-4619-9D53-80F4E185078A Q36127308-A8242275-9FD5-49A6-9065-71D362D72190 Q36413157-E43060F0-93FE-4C13-8695-466DE7CC8FAD

P2860

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

http://www.wikidata.org/entity/Q24546291

description

2006 nî lūn-bûn

@nan

2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Dominant-negative inhibition o ...... invasion and prolongs survival

@ast

Dominant-negative inhibition o ...... invasion and prolongs survival

@en

Dominant-negative inhibition o ...... invasion and prolongs survival

@nl

type

label

Dominant-negative inhibition o ...... invasion and prolongs survival

@ast

Dominant-negative inhibition o ...... invasion and prolongs survival

@en

Dominant-negative inhibition o ...... invasion and prolongs survival

@nl

prefLabel

Dominant-negative inhibition o ...... invasion and prolongs survival

@ast

Dominant-negative inhibition o ...... invasion and prolongs survival

@en

Dominant-negative inhibition o ...... invasion and prolongs survival

@nl

P1433

Q24546291-E4C78830-8BE0-4BD5-BAC5-D42BC9403DF2

P1476

Q24546291-C623ED4D-E0F9-4200-9A96-AB71BABAA93E

P2093

Q24546291-10E387D5-69EB-4174-86C8-D8E41825D511

Q24546291-1BA91557-73D3-4972-A864-29BB8C027FE5

Q24546291-263DDEF5-E266-494B-B559-75ED444962F0

Q24546291-46641F76-C4C1-42A8-9C5D-F636488D1E24

Q24546291-6311DD71-0266-4EBB-BAD2-F9165D331909

Q24546291-66EB96A2-E753-46D9-A5C8-C3149F660FCF

Q24546291-83788280-DD0C-4FD2-962E-9FA8814B5525

Q24546291-A31105A8-6BFD-4E24-A35B-39533658D6FE

Q24546291-D0F2CABD-6211-4D0A-ABFE-84B175FEE7FE

Q24546291-D71FC401-8150-4CF5-B849-FBCA4DB5BA44

P2860

Q24546291-0D845107-3703-4F80-9F8C-03F71633B42B

Q24546291-15D1A114-6E2E-4C94-BB20-94513B251385

Q24546291-1F9FF505-ABDC-46FA-8EB7-8CA9BDB68CE1

Q24546291-2AEA8926-F44F-442E-A1A9-3BFBFF7C91C5

Q24546291-3870757F-4767-43B0-9358-7354A7FC184B

Q24546291-392C4E7A-94B2-4B34-91EF-17167391A781

Q24546291-4283CD93-982C-4F72-B11C-F04C59A389CB

Q24546291-44864A2C-59CC-49E7-B451-2C4F05318B34

Q24546291-5D64BBCC-6B99-4B37-8F71-6CDA6E3A45E2

Q24546291-60100CA0-7CA8-4BF0-B733-E34D10DC5E12

P304

Q24546291-69FD9FE0-9921-4845-B4B7-3BC309C7B0CB

P31

Q24546291-CB0681C7-D341-4DE5-BBB3-E0AE0454F1DF

P356

Q24546291-C68A1204-5C68-47AD-B1AA-5FBAEA39ED60

P407

Q24546291-2721E022-5B57-45E8-948F-EDE6B4CE91EA

P433

Q24546291-AF07455D-7870-4D0E-B01B-2719B1811A7C

P478

Q24546291-AB17C978-03E9-4E67-B843-693863A072E9

P50

Q24546291-69594537-D802-463B-9E07-0FA8C4A3D993

P577

Q24546291-93A38ED2-32AB-4884-BA41-C376812AB1CE

P5875

Q24546291-59CD2CFE-965E-4BDD-BF57-CC935742DCF7

P698

Q24546291-32A5E5AF-86BE-4DB1-A78D-18163A6A7F50

P921

Q24546291-0E1419D6-2D92-4561-B85C-966C500E56E9

P932

Q24546291-632660D1-F291-4881-B310-3D03C0FA1B5E

P356

PNAS.0510923103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Dominant-negative inhibition o ...... invasion and prolongs survival

@en

P2093

Andrea Kunkel

http://www.w3.org/2001/XMLSchema#string

Axel Ullrich

http://www.w3.org/2001/XMLSchema#string

Fabian Kiessling

http://www.w3.org/2001/XMLSchema#string

Hans-Holger Capelle

http://www.w3.org/2001/XMLSchema#string

Marco Essig

http://www.w3.org/2001/XMLSchema#string

Peter Vajkoczy

http://www.w3.org/2001/XMLSchema#string

Pjotr Knyazev

http://www.w3.org/2001/XMLSchema#string

Ralf Erber

http://www.w3.org/2001/XMLSchema#string

Sandra Behrndt

http://www.w3.org/2001/XMLSchema#string

Tracy-Ann Read

http://www.w3.org/2001/XMLSchema#string

P2860

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

Signal transduction by receptors with tyrosine kinase activity

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

A novel putative tyrosine kinase receptor with oncogenic potential

The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage

Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation

Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2.

Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system.

The Gas6/Axl system: a novel regulator of vascular cell function.

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.

P304

5799-804

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0510923103

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

103

http://www.w3.org/2001/XMLSchema#string

P50

Hendrik von Tengg-Kobligk

P577

2006-04-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7193654

http://www.w3.org/2001/XMLSchema#string

P698

16585512

http://www.w3.org/2001/XMLSchema#string

P921

P932

1458653

http://www.w3.org/2001/XMLSchema#string