Therapeutic implications of the emerging molecular biology of uveal melanoma. - Wikidata - wikimedia - TriplyDB

Therapeutic implications of the emerging molecular biology of uveal melanoma.

Therapeutic implications of the emerging molecular biology of uveal melanoma.

http://www.wikidata.org/entity/Q34173920

about

Uveal Melanoma Patient-Derived Xenografts Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)Adjuvant Therapy of Uveal Melanoma: Current Status Metastatic uveal melanoma: biology and emerging treatments Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.The genetics of uveal melanoma: current insights Genome-wide profiling is a clinically relevant and affordable prognostic test in posterior uveal melanoma.A molecular revolution in uveal melanoma: implications for patient care and targeted therapy The phosphoinositide 3-kinase α selective inhibitor BYL719 enhances the effect of the protein kinase C inhibitor AEB071 in GNAQ/GNA11-mutant uveal melanoma cells.The genetics of uveal melanoma: an emerging framework for targeted therapy High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.Phase II trial of sorafenib in combination with carboplatin and paclitaxel in patients with metastatic uveal melanoma: SWOG S0512.Ocular melanoma: an overview of the current status.Translational models of ocular disease.Molecular bases of cutaneous and uveal melanomas.Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq.Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles.Ex vivo enrichment of circulating anti-tumor T cells from both cutaneous and ocular melanoma patients: clinical implications for adoptive cell transfer therapy Genetics of primary intraocular tumors Molecular pathology of uveal melanoma The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma.Systemic treatment of metastatic uveal melanoma: review of literature and future perspectives Phase II randomised discontinuation trial of the MET/VEGF receptor inhibitor cabozantinib in metastatic melanoma.Melanoma mutagenesis and aberrant cell signaling.Genetic determinants of uveal melanoma.The biology and clinical development of MEK inhibitors for cancer.Patient-derived xenografts recapitulate molecular features of human uveal melanomas.Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma.Update on Metastatic Uveal Melanoma: Progress and Challenges.Selumetinib for the treatment of metastatic uveal melanoma: past and future perspectives.P2RX7-V3 is a novel oncogene that promotes tumorigenesis in uveal melanoma.Assessing Prognosis in Uveal Melanoma.Rare tumors: an eye on the future.Ocular oncology: advances in retinoblastoma, uveal melanoma and conjunctival melanoma.Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma.Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner.Skin metastases in metastatic uveal melanoma: GNAQ/GNA11 mutational analysis as a valuable tool.Uveal melanoma.

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P2860

Therapeutic implications of the emerging molecular biology of uveal melanoma.

http://www.wikidata.org/entity/Q34173920

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Therapeutic implications of the emerging molecular biology of uveal melanoma.

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

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type

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

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prefLabel

Therapeutic implications of the emerging molecular biology of uveal melanoma.

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Therapeutic implications of the emerging molecular biology of uveal melanoma.

@en

Therapeutic implications of the emerging molecular biology of uveal melanoma.

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1078-0432.CCR-10-3169

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Clinical Cancer Research

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Therapeutic implications of the emerging molecular biology of uveal melanoma

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David H Abramson

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Gary K Schwartz

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Jedd D Wolchok

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Mrinali Patel

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Paul B Chapman

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Richard D Carvajal

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2087-2100

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10.1158/1078-0432.CCR-10-3169

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Elizabeth C Smyth

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234109982

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