Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
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Deregulation of RGS2 in cardiovascular diseasesThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsRegulator of G Protein Signaling 2: A Versatile Regulator of Vascular FunctionCholinergic activity as a new target in diseases of the heartStructural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunitsStructural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq ComplexRegulators of G-protein signaling in the heart and their potential as therapeutic targets.Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth musclesRGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signalingRegulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in miceIdentification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercrossFBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex.Structure of the Regulator of G Protein Signaling 8 (RGS8)-Gαq Complex: MOLECULAR BASIS FOR Gα SELECTIVITY.The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signalingVascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets.Two Galpha(i1) rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activityRGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury.Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal modelNon-dipping and arterial hypertension depend on clinical factors rather than on genetic variability of ACE and RGS2 genes in patients with type 1 diabetes.Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study.Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.Renal actions of RGS2 control blood pressure.Regulator of G-protein signaling 4 suppresses LPS-induced MUC5AC overproduction in the airway.Does airway smooth muscle express an inflammatory phenotype in asthma?Knowledge-based compact disease models identify new molecular players contributing to early-stage Alzheimer's disease.RGS2: a "turn-off" in hypertensionRegulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses.Regulators of G protein signalling: potential targets for treatment of allergic inflammatory diseases such as asthma.Anthrax lethal toxin-induced gene expression changes in mouse lung.Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transductionSensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior.β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoidsRegulation of Renal Hemodynamics and Function by RGS2.
P2860
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P2860
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@ast
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@en
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@nl
type
label
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@ast
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@en
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@nl
prefLabel
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@ast
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@en
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@nl
P2093
P2860
P356
P1476
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
@en
P2093
Anthony J Muslin
Antonio Oliveira-dos-Santos
J Michael Wyss
Josef M Penninger
Kendall J Blumer
Kevin M Kaltenbronn
Man-Hee Rhee
Robert P Mecham
Russell H Knutsen
P2860
P304
P356
10.1172/JCI15598
P407
P577
2003-02-01T00:00:00Z