about
Activation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressorNeoadjuvant therapy for early-stage breast cancer: the clinical utility of pertuzumabPI3K/Akt/mTOR inhibitors in breast cancerThe PI3K/AKT Pathway and Renal Cell CarcinomaGSK-3 as potential target for therapeutic intervention in cancerAdvances in targeting signal transduction pathwaysCharacterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinaseMolecular identification for epigallocatechin-3-gallate-mediated antioxidant intervention on the H2O2-induced oxidative stress in H9c2 rat cardiomyoblastsTwo hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.Estrogen receptor alpha prevents bladder cancer via INPP4B inhibited akt pathway in vitro and in vivo.Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activitiesIdentification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cellsAn integrative analysis of PIK3CA mutation, PTEN, and INPP4B expression in terms of trastuzumab efficacy in HER2-positive breast cancerDiscovery and development of small molecule SHIP phosphatase modulators.Phosphatases: the new brakes for cancer development?Expression of ERG protein in prostate cancer: variability and biological correlates.Elevated PI3K signaling drives multiple breast cancer subtypes.Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancerExpression and transcriptional profiling of the LKB1 tumor suppressor in cervical cancer cellsEctopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberineGenomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway.Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung.Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation.Targeting the PI3K pathway for cancer therapy.Inpp4b is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis.Role of inositol poly-phosphatases and their targets in T cell biology.The extended human PTPome: a growing tyrosine phosphatase family.INPP4B-mediated DNA repair pathway confers resistance to chemotherapy in acute myeloid leukemia.Mir-765 promotes cell proliferation by downregulating INPP4B expression in human hepatocellular carcinoma.INPP4B suppresses prostate cancer cell invasionPI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment.INPP4B overexpression enhances the antitumor efficacy of PARP inhibitor AG014699 in MDA-MB-231 triple-negative breast cancer cells.The ZnR/GPR39 interacts with the CaSR to enhance signaling in prostate and salivary epithelia.How does SHIP1/2 balance PtdIns(3,4)P2 and does it signal independently of its phosphatase activity?Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapyMechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks.INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia.The Extended Family of Protein Tyrosine Phosphatases.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
INPP4B: the new kid on the PI3K block.
@ast
INPP4B: the new kid on the PI3K block.
@en
INPP4B: the new kid on the PI3K block.
@nl
type
label
INPP4B: the new kid on the PI3K block.
@ast
INPP4B: the new kid on the PI3K block.
@en
INPP4B: the new kid on the PI3K block.
@nl
prefLabel
INPP4B: the new kid on the PI3K block.
@ast
INPP4B: the new kid on the PI3K block.
@en
INPP4B: the new kid on the PI3K block.
@nl
P2093
P2860
P356
P1433
P1476
INPP4B: the new kid on the PI3K block.
@en
P2093
Irina U Agoulnik
Michael M Ittmann
Myles C Hodgson
Wayne A Bowden
P2860
P304
P356
10.18632/ONCOTARGET.260
P407
P5008
P577
2011-04-01T00:00:00Z