Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta.
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Unfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic ImplicationsThe nucleotide exchange factors of Hsp70 molecular chaperonesDisaggregases, molecular chaperones that resolubilize protein aggregatesA Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum MembraneAn essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic developmentTherapeutic inducers of the HSP70/HSP110 protect mice against traumatic brain injuryTau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Hierarchical functional specificity of cytosolic heat shock protein 70 (Hsp70) nucleotide exchange factors in yeast.Metazoan Hsp70 machines use Hsp110 to power protein disaggregationNeuroGeM, a knowledgebase of genetic modifiers in neurodegenerative diseasesMolecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.Heat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis.Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1.Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline and trehalose.Molecular chaperones and neuronal proteostasis.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Turnover of C99 is controlled by a crosstalk between ERAD and ubiquitin-independent lysosomal degradation in human neuroglioma cells.Designer protein disaggregases to counter neurodegenerative disease.The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease.Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities.Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis in vivo.The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins.Perspectives in molecular imaging using staging biomarkers and immunotherapies in Alzheimer's disease.
P2860
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P2860
Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@ast
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@en
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@nl
type
label
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@ast
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@en
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@nl
prefLabel
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@ast
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@en
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@nl
P2093
P2860
P356
P1476
Loss of Hsp110 leads to age-de ...... ion of insoluble amyloid beta.
@en
P2093
Binnur Eroglu
Demetrius Moskophidis
Nahid F Mivechi
P2860
P304
P356
10.1128/MCB.01493-09
P407
P577
2010-08-02T00:00:00Z