The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology.
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Neural restrictive silencer factor and choline acetyltransferase expression in cerebral tissue of Alzheimer's Disease patients: A pilot studyEffect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review)Propofol directly increases tau phosphorylationSynaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating propertyMetformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice.Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Differential growth factor regulation of aspartyl-(asparaginyl)-beta-hydroxylase family genes in SH-Sy5y human neuroblastoma cells.Interleukin-3 prevents neuronal death induced by amyloid peptideType II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells.Telling tails.A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation.Purkinje Cell Pathology and Loss in Multiple Sclerosis Cerebellum.Discovery of thienoquinolone derivatives as selective and ATP non-competitive CDK5/p25 inhibitors by structure-based virtual screeningProteomic identification of proteins suggestive of immune-mediated response or neuronal degeneration in serum of achalasia patientsRoles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.Neuroprotective strategies against calpain-mediated neurodegeneration.Regulation of Sox6 by cyclin dependent kinase 5 in brainHypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors.The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and PathologyA truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice.Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processingCell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches.Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35.Anesthesia and tau pathology.Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila modelAcceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia.Activation of cyclin-dependent kinase 5 mediates orofacial mechanical hyperalgesia.Functional and structural effects of amyloid-β aggregate on Xenopus laevis oocytes.Neurofilamentopathy in neurodegenerative diseasesNeurogenesis in Alzheimer´s disease: a realistic alternative to neuronal degeneration?Cellular senescence requires CDK5 repression of Rac1 activity.Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.Novel rare variations in genes that regulate developmental change in N-methyl-d-aspartate receptor in patients with schizophrenia.
P2860
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P2860
The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@ast
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@en
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@nl
type
label
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@ast
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@en
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@nl
prefLabel
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@ast
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@en
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@nl
P2093
P1433
P1476
The protein kinase Cdk5. Struc ...... ment in Alzheimer's pathology.
@en
P2093
P304
P356
10.1046/J.1432-1033.2001.02024.X
P407
P577
2001-03-01T00:00:00Z