Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa.
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Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infectionsPhylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic featureType I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structureX-ray Structure of 4,4'-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14 -Demethylase (CYP51)Trypanosoma cruzi CYP51 Inhibitor Derived from a Mycobacterium tuberculosis Screen HitStructural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and FluconazoleStructural Insights into Inhibition of Sterol 14 -Demethylase in the Human Pathogen Trypanosoma cruziIdentification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl ReductaseComplexes of Trypanosoma cruzi Sterol 14 -Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease: STRUCTURAL BASIS FOR PATHOGEN SELECTIVITYCrystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loopReprogramming neutral lipid metabolism in mouse dendritic leucocytes hosting live Leishmania amazonensis amastigotesCYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovaniDiverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51Trypanosoma cruzi response to sterol biosynthesis inhibitors: morphophysiological alterations leading to cell deathGenetic profiling of the isoprenoid and sterol biosynthesis pathway genes of Trypanosoma cruziTrypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental ModelNovel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream formsSterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasisBioinformatic Analysis of Leishmania donovani Long-Chain Fatty Acid-CoA Ligase as a Novel Drug TargetBiological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathwayDrug resistance in leishmaniasisDelivery of antimicrobials into parasitesTranscriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes.Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella.Ergosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria.Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.Silicon phthalocyanine 4 phototoxicity in Trichophyton rubrum.A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major.A nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection.Vitamin C biosynthesis in trypanosomes: a role for the glycosome.Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisome.Drug strategies targeting CYP51 in neglected tropical diseasesFunctional characterization of a fatty acyl-CoA-binding protein (ACBP) from the apicomplexan Cryptosporidium parvum.New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.Therapeutic switching in leishmania chemotherapy: a distinct approach towards unsatisfied treatment needs.Trypanosoma brucei: inhibition of acetyl-CoA carboxylase by haloxyfopComparison of sterols and fatty acids in two species of Ganoderma.Current progress in the fatty acid metabolism in Cryptosporidium parvum.Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole.Parasite plastids: approaching the endgame.
P2860
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P2860
Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@ast
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@en
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@nl
type
label
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@ast
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@en
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@nl
prefLabel
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@ast
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@en
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@nl
P2093
P1476
Fatty acid and sterol metaboli ...... anosomatid parasitic protozoa.
@en
P2093
P304
P356
10.1016/S0166-6851(02)00280-3
P577
2003-02-01T00:00:00Z