Large-scale conformational dynamics of the HIV-1 integrase core domain and its catalytic loop mutants
about
Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)Molecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structuresThe role of oligomerization and cooperative regulation in protein function: the case of tryptophan synthaseRevealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsChemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan InteractionsSolution conformation and dynamics of the HIV-1 integrase core domain.Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptorsDDE transposases: Structural similarity and diversityDynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation.Effect of raltegravir resistance mutations in HIV-1 integrase on viral fitnessBinding modes of diketo-acid inhibitors of HIV-1 integrase: a comparative molecular dynamics simulation study.Hybrid quantum mechanical/molecular mechanical molecular dynamics simulations of HIV-1 integrase/inhibitor complexes.Differential impact of resistance-associated mutations to protease inhibitors and nonnucleoside reverse transcriptase inhibitors on HIV-1 replication capacityProline substitution of dimer interface β-strand residues as a strategy for the design of functional monomeric proteins.Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs.Molecular dynamics of HIV1-integrase in complex with 93del - a structural perspective on the mechanism of inhibition.Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore.A quantum mechanic/molecular mechanic study of the wild-type and N155S mutant HIV-1 integrase complexed with diketo acid.Study on the interactions between diketo-acid inhibitors and prototype foamy virus integrase-DNA complex via molecular docking and comparative molecular dynamics simulation methods.Communications: Electron polarization critically stabilizes the Mg2+ complex in the catalytic core domain of HIV-1 integrase.Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions
P2860
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P2860
Large-scale conformational dynamics of the HIV-1 integrase core domain and its catalytic loop mutants
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Large-scale conformational dyn ...... and its catalytic loop mutants
@ast
Large-scale conformational dyn ...... and its catalytic loop mutants
@en
Large-scale conformational dyn ...... and its catalytic loop mutants
@nl
type
label
Large-scale conformational dyn ...... and its catalytic loop mutants
@ast
Large-scale conformational dyn ...... and its catalytic loop mutants
@en
Large-scale conformational dyn ...... and its catalytic loop mutants
@nl
prefLabel
Large-scale conformational dyn ...... and its catalytic loop mutants
@ast
Large-scale conformational dyn ...... and its catalytic loop mutants
@en
Large-scale conformational dyn ...... and its catalytic loop mutants
@nl
P2093
P2860
P1433
P1476
Large-scale conformational dyn ...... and its catalytic loop mutants
@en
P2093
Jinxia Deng
Matthew C Lee
P2860
P304
P356
10.1529/BIOPHYSJ.104.058446
P407
P577
2005-02-24T00:00:00Z