Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. - Wikidata - wikimedia - TriplyDB

Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.

Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.

http://www.wikidata.org/entity/Q34191681

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Hedgehog Signaling in Pancreatic Fibrosis and Cancer Hedgehog Signaling in the Maintenance of Cancer Stem Cells Dynamics and precision in retinoic acid morphogen gradients Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity Regulation by miR181 family of the dependence receptor CDON tumor suppressive activity in neuroblastoma Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon Smoothened goes molecular: new pieces in the hedgehog signaling puzzle Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors.Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand Ptch2 mediates the Shh response in Ptch1-/- cells.Sonic hedgehog signaling in the lung. From development to disease.CDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signaling Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties.Dampening the signals transduced through hedgehog via microRNA miR-7 facilitates notch-induced tumourigenesis.Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice.Gas1 is a receptor for sonic hedgehog to repel enteric axons.The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.Fgfr2 is integral for bladder mesenchyme patterning and function Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation.Inductive specification and axonal orientation of spinal neurons mediated by divergent bone morphogenetic protein signaling pathways Overweight in mice and enhanced adipogenesis in vitro are associated with lack of the hedgehog coreceptor boc.Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function Computational prediction and experimental validation of novel Hedgehog-responsive enhancers linked to genes of the Hedgehog pathway Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.Hedgehog secretion and signal transduction in vertebrates.Regulation of Hedgehog signaling by ubiquitination.Recurrent HERV-H-mediated 3q13.2-q13.31 deletions cause a syndrome of hypotonia and motor, language, and cognitive delays.Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.

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Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.

http://www.wikidata.org/entity/Q34191681

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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J.DEVCEL.2011.04.018

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Developmental Cell

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Overlapping roles and collecti ...... d BOC in SHH pathway function.

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Andrew P McMahon

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Benjamin L Allen

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Frédéric Charron

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Irene W Althaus

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Jane Y Song

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Jong-Sun Kang

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Luisa Izzi

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Robert S Krauss

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Characterization of two patched receptors for the vertebrate hedgehog protein family

Activating Smoothened mutations in sporadic basal-cell carcinoma

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafish

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system

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10.1016/J.DEVCEL.2011.04.018

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