Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development
about
Research Advances on Pathways of Nickel-Induced ApoptosisLoss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia.Regulation of platelet lifespan by apoptosis.Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1).The essential role of evasion from cell death in cancer.MCL1 increases primitive thymocyte viability in female mice and promotes thymic expansion into adulthoodRegulation of memory B-cell survival by the BH3-only protein Puma.BH3-only proteins in apoptosis at a glanceBcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cellsThe BCL-2 protein family, BH3-mimetics and cancer therapy.Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf.Possible pitfalls investigating cell death responses in genetically engineered mouse models and derived cell lines.RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice.Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisDeregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.Deciphering the rules of programmed cell death to improve therapy of cancer and other diseasesThe role of the apoptotic machinery in tumor suppression.Bcl-2 proteins in development, health, and disease of the hematopoietic system.Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα--14-3-3ζ] association.Deletion of Irf5 protects hematopoietic stem cells from DNA damage-induced apoptosis and suppresses γ-irradiation-induced thymic lymphomagenesis.Protein kinase A determines platelet life span and survival by regulating apoptosis.Mechanisms of platelet clearance and translation to improve platelet storage.
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P2860
Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
Individual and overlapping rol ...... of thymic lymphoma development
@ast
Individual and overlapping rol ...... of thymic lymphoma development
@en
Individual and overlapping rol ...... of thymic lymphoma development
@nl
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Individual and overlapping rol ...... of thymic lymphoma development
@ast
Individual and overlapping rol ...... of thymic lymphoma development
@en
Individual and overlapping rol ...... of thymic lymphoma development
@nl
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Individual and overlapping rol ...... of thymic lymphoma development
@ast
Individual and overlapping rol ...... of thymic lymphoma development
@en
Individual and overlapping rol ...... of thymic lymphoma development
@nl
P2093
P2860
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P356
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Individual and overlapping rol ...... of thymic lymphoma development
@en
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M W Goschnick
S A Kinkel
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P2888
P304
P356
10.1038/CDD.2010.43
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P577
2010-04-30T00:00:00Z