The BCL-2 protein family, BH3-mimetics and cancer therapy.
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Chondrocyte Apoptosis in the Pathogenesis of OsteoarthritisHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyDiscovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based MethodsUpregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.Bcl-2 homologue Debcl enhances α-synuclein-induced phenotypes in Drosophila.The Bcl-2 homologue Buffy rescues α-synuclein-induced Parkinson disease-like phenotypes in Drosophila.Cancer Therapy Due to Apoptosis: Galectin-9.Synthesis, characterization, DNA binding, cleavage activity, cytotoxicity and molecular docking of new nano water-soluble [M(5-CH₂PPh₃-3,4-salpyr)](ClO₄)₂ (M = Ni, Zn) complexes.Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1).Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway.The Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression.Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced HepatocarcinogenesisThe microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1.Tissue-specific tumorigenesis: context matters.MiR-181a influences the cognitive function of epileptic rats induced by pentylenetetrazol.Biphasic regulation of InsP3 receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability.Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines.Development of a lytic peptide derived from BH3-only proteinsRAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice.Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway.Impact of loss of BH3-only proteins on the development and treatment of MLL-fusion gene-driven AML in mice.A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis.The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.Targeting prohibitins induces apoptosis in acute myeloid leukemia cells.Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer.Resistance to Cell Death and Its Modulation in Cancer Stem Cells.Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.The therapeutic effect of death: Newcastle disease virus and its antitumor potential.Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids.Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway.CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia.Bcl-2 proteins in development, health, and disease of the hematopoietic system.MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis.(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.Targeting childhood, adolescent and young adult non-Hodgkin lymphoma: therapeutic horizons.
P2860
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P2860
The BCL-2 protein family, BH3-mimetics and cancer therapy.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@ast
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@en
type
label
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@ast
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@en
prefLabel
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@ast
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@en
P2860
P356
P1476
The BCL-2 protein family, BH3-mimetics and cancer therapy.
@en
P2093
A R D Delbridge
P2860
P2888
P304
P356
10.1038/CDD.2015.50
P577
2015-05-08T00:00:00Z