The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines. - Wikidata - wikimedia - TriplyDB

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

http://www.wikidata.org/entity/Q34192894

about

ADCY5 couples glucose to insulin secretion in human islets MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research Regulation of Bim in Health and Disease Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools Zinc transporter 8 (ZnT8) and β cell function Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus Concise review: in search of unlimited sources of functional human pancreatic beta cells Transcriptional and epigenetic regulation in human islets Transcriptional regulation of chemokine genes: a link to pancreatic islet inflammation?Islet inflammation in plain sight The streetlight effect in type 1 diabetes The diabetes susceptibility gene Clec16a regulates mitophagy GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance FIDEA: a server for the functional interpretation of differential expression analysis Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance.Pharmacogenomics of Drug Response in Type 2 Diabetes: Toward the Definition of Tailored Therapies?Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.The pancreatic β-cell transcriptome and integrated-omics.Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy.The transcriptomes of the crucian carp complex (Carassius auratus) provide insights into the distinction between unisexual triploids and sexual diploids.CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.A SNP in intron 8 of CD46 causes a novel transcript associated with mastitis in Holsteins Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism Nova1 is a master regulator of alternative splicing in pancreatic beta cells.Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.Transcription factors that convert adult cell identity are differentially polycomb repressed The human pancreas proteome defined by transcriptomics and antibody-based profiling.Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes.Clic4, a novel protein that sensitizes β-cells to apoptosis ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion.Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1 Analysis artefacts of the INS-IGF2 fusion transcript.Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells The TrxG Complex Mediates Cytokine Induced De Novo Enhancer Formation in Islets.Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes.

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The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

http://www.wikidata.org/entity/Q34192894

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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JOURNAL.PGEN.1002552

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Décio L Eizirik

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Giorgia Sisino

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Guy Bottu

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Jenny Barthson

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Linda Hughes

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Lorna Gregory

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Luc Bouwens

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Maikel L Colli

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Mariana Igoillo-Esteve

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Thomas Bouckenooghe

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P2860

Most "dark matter" transcripts are associated with known genes

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

RNA-Seq: a revolutionary tool for transcriptomics

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

The transcriptional landscape of the yeast genome defined by RNA sequencing

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

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e1002552

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10.1371/JOURNAL.PGEN.1002552

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3

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8

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Piero Marchetti

Michael Sammeth

Lorella Marselli

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2012-03-08T00:00:00Z

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221698152

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22412385

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type-1 diabetes

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3297576

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