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Targeted genome modification in mice using zinc-finger nucleases

Targeted genome modification in mice using zinc-finger nucleases

http://www.wikidata.org/entity/Q34196443

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Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes Targeting DNA With Fingers and TALENs Precision editing of large animal genomes Gene targeting in the rat: advances and opportunities Applications of CRISPR-Cas systems in neuroscience Origins of Programmable Nucleases for Genome Engineering From Gene Targeting to Genome Editing: Transgenic animals applications and beyond Genome-editing tools for stem cell biology Genetics in non-genetic model systems Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats Simple Genome Editing of Rodent Intact Embryos by Electroporation Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis Genome Engineering With Zinc-Finger Nucleases Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight.Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems.p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing.A single blastocyst assay optimized for detecting CRISPR/Cas9 system-induced indel mutations in mice Heritable targeted inactivation of myostatin gene in yellow catfish (Pelteobagrus fulvidraco) using engineered zinc finger nucleases.Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases.Generation of improved humanized mouse models for human infectious diseases.Mouse genome engineering using designer nucleases.TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery.Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat.Systems Biology-Derived Discoveries of Intrinsic Clocks.High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing Direct cloning of isogenic murine DNA in yeast and relevance of isogenicity for targeting in embryonic stem cells.Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA A novel genetic system based on zinc finger nucleases for the identification of interactions between proteins in vivo.Targeted genome engineering via zinc finger nucleases CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development.Genetically engineered humanized mouse models for preclinical antibody studies.Rapid prototyping of microbial cell factories via genome-scale engineering.

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Targeted genome modification in mice using zinc-finger nucleases

http://www.wikidata.org/entity/Q34196443

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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type

label

Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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prefLabel

Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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Targeted genome modification in mice using zinc-finger nucleases

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Anne Harrington

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Diana Ji

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Edward J Weinstein

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Iara D Carbery

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Lucy Liaw

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Victoria Brown

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Xiaoxia Cui

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P2860

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

DNA resection in eukaryotes: deciding how to fix the break

Genetic transformation of mouse embryos by microinjection of purified DNA

Knockout rats via embryo microinjection of zinc-finger nucleases

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

High-frequency modification of plant genes using engineered zinc-finger nucleases

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains

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