Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
about
Cell cycle-specific function of Ikaros in human leukemiaSequence variants affecting eosinophil numbers associate with asthma and myocardial infarctionInactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiencyHelios expression coordinates the development of a subset of striatopallidal medium spiny neuronsIkaros transcription factors: flying between stress and inflammation.Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.Transcription Factor Networks derived from Breast Cancer Stem Cells control the immune response in the Basal subtype.Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genesA role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cellsThe combined expression patterns of Ikaros isoforms characterize different hematological tumor subtypesRate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4.Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons.Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.Apigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer.HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.Ikaros expression sensitizes leukemic cells to the chemotherapeutic drug doxorubicinIkaros and acute leukemia.Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.The endocannabinoid system and sex steroid hormone-dependent cancers.The genomic landscape of hypodiploid acute lymphoblastic leukemia.COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia.Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL.IKZF1: a critical role in the pathogenesis of systemic lupus erythematosus?Transcription factors involved in the regulation of natural killer cell development and function: an update.Expression of different functional isoforms in haematopoiesis.Helios Enhances Treg Cell Function in Cooperation With FoxP3.A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromesDirect protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cellsEctopic Ikaros expression positively correlates with lung cancer progression.Significance of Inactivated Genes in Leukemia: Pathogenesis and PrognosisControl of immune-mediated pathology via the aryl hydrocarbon receptor.Expression of dominant-negative Ikaros isoforms and associated genetic alterations in Chinese adult patients with leukemia.Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP.Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels.The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros.Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.Expression of Helios in gastric tumor cells predicts better survival in gastric cancer patients.Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients
P2860
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P2860
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@ast
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@en
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@nl
type
label
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@ast
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@en
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@nl
prefLabel
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@ast
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@en
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@nl
P2860
P1476
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.
@en
P2093
Angelita Rebollo
Christian Schmitt
P2860
P304
P356
10.1046/J.1440-1711.2003.01159.X
P577
2003-06-01T00:00:00Z