Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. - Wikidata - wikimedia - TriplyDB

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

http://www.wikidata.org/entity/Q34198217

about

Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy Oxidative stress, bone marrow failure, and genome instability in hematopoietic stem cells Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models Diseases associated with defective responses to DNA damage The inherited bone marrow failure syndromes Fanconi anemia and the cell cycle: new perspectives on aneuploidy Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases BLM protein mitigates formaldehyde-induced genomic instability Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51 Fancf-deficient mice are prone to develop ovarian tumours Fanconi anaemia and the repair of Watson and Crick DNA crosslinks Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene Parallel functional changes in independent testis-specific duplicates of Aldehyde dehydrogenase in Drosophila Central nervous system abnormalities in Fanconi anaemia: patterns and frequency on magnetic resonance imaging.The human microbiota associated with overall health.Ethanol itself is a holoprosencephaly-inducing teratogen.A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms The genetic and biochemical basis of FANCD2 monoubiquitination Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors.Dark Hydrazone Fluorescence Labeling Agents Enable Imaging of Cellular Aldehydic Load.The endogenous exposome.Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Metabolic regulation of stem cell function.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair Metabolism: alcohol, DNA and disease.Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.Maternal aldehyde elimination during pregnancy preserves the fetal genome Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

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P2860

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

http://www.wikidata.org/entity/Q34198217

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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type

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

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Frédéric Langevin

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Gerry P Crossan

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Ivan V Rosado

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Ketan J Patel

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Mark J Arends

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P2860

The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption

Instability and decay of the primary structure of DNA

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

Mouse models of Fanconi anemia

Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells.

P2888

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10.1038/NATURE10192

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7354

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1052088101

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21734703

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