Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
about
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatinDisruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemiaHow the fanconi anemia pathway guards the genome3p-- syndrome defines a hearing loss locus in 3p25.3Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathwayMutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer.Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsUpdate of the human and mouse Fanconi anemia genesOxidative stress, bone marrow failure, and genome instability in hematopoietic stem cellsLearning from a paradox: recent insights into Fanconi anaemia through studying mouse modelsMammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesisMouse models of Fanconi anemiaFancf-deficient mice are prone to develop ovarian tumoursCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsUncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesisUbiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instabilityHES1 is a novel interactor of the Fanconi anemia core complexA reduction of licensed origins reveals strain-specific replication dynamics in miceDeletion of Fanca or Fancd2 dysregulates Treg in miceConcomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalusFancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in miceCharacterizing a rat Brca2 knockout modelLoss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouseThe Fanconi anemia pathway and ubiquitinHuman RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signalingSignificance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancerLarge deletion causing von Hippel-Lindau disease and hereditary breast cancer syndrome.Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repairFancd2 counteracts the toxic effects of naturally produced aldehydes in mice.Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.Menin and p53 have non-synergistic effects on tumorigenesis in miceDeficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancerDNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents.
P2860
Q24563629-04A47C01-86E6-41F2-B41E-53E77CEC982FQ24634306-454AA9C9-E950-47FC-8F73-5D2B4DAFF0C2Q24634556-722D0B97-536C-4537-8AA7-98A24F17D0B3Q24680366-ADC34EB8-75B4-4DE8-96B1-27D74B9C1A74Q24683360-580105F1-A0E2-4297-9C2E-61AAC158E1ABQ25257392-8F697642-F789-436A-A95D-524313308A02Q26740026-85DEB847-3A86-4BE2-9151-A72EFD90DB35Q26776461-5668A21C-4EA2-45B3-8E49-200491A979D3Q26823605-1F98974D-CD44-424F-8798-347CE8B87B10Q26863356-92D36278-9C93-4D47-907E-3D13CAD712EBQ27340183-44CAB45E-1CC9-469F-8C78-7387803A19C3Q28244296-4F1768E0-C921-4846-99E6-266E333B0901Q28247935-5C6EDAC7-BD38-4B03-90E1-C9D7993F4A21Q28252640-91B4A567-A5BA-40E1-9068-AABC1F9A2B22Q28267862-939CAC7A-F743-42B1-8F72-4884980B9AFDQ28272401-D201772A-F1F9-4C96-AB4F-D251DB523FE7Q28283737-1EF04B2A-5862-4103-BBE5-2DBD6859B52EQ28507067-66008898-8D92-4B92-ABE7-276CEAEC4318Q28507762-02A688B5-5EA9-49CE-9ED7-EF97EE06DD05Q28512938-C37027B8-D249-4C03-BB8A-5E0EE89B8E4CQ28513158-D48FABD4-EC16-488B-80D4-62F6056F7815Q28584347-DD7EC7ED-69C7-4F6E-875C-828629313E08Q28586626-D9A4905D-3DD3-4A2C-8121-D58749ED85DFQ28756516-DE5D6062-761A-473C-8347-587EA758C765Q33309941-E407BA62-72C8-4674-AD3F-E01C7344B3A5Q33551464-E0EA88DB-A70A-4F1A-9AED-E475B3A2F100Q33561045-1E15338C-10D5-4933-AB93-4DFDEADBC758Q33880788-0B0A4C7D-E55B-4713-8013-9875B28ABEE4Q33882536-8480D156-488C-4242-AF99-4A8DC34966F3Q33994507-04E9D978-4C43-4932-9E8C-45787D89BAE6Q34023194-4496D805-CF51-4878-80B0-CB8A82AEC531Q34115459-92C2CF5B-C6ED-468D-A844-49E09BED6163Q34198217-DC9D2AE5-FF03-4C25-9906-A36E5E81F49EQ34295969-FA277BA7-EE85-4971-9B43-D9CA352F91F6Q34307740-93CA6933-9AB4-4301-A12A-38C0F29342B7Q34393686-8647A53E-3251-44A0-8208-7D550138F928Q34396087-509D7096-C673-4F41-A569-60BF2B0202A3Q34482867-D22FA989-9616-442C-9DAA-D14740638E5EQ34495943-A0A833A8-3FBA-4145-A909-775099A71492Q34659090-7488C689-19A7-4756-81B6-7DF68C59FD24
P2860
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@ast
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@en
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@nl
type
label
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@ast
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@en
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@nl
prefLabel
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@ast
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@en
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
@en
P2093
M Stephen Meyn
Meenakshi Noll
Milton J Finegold
Scott Houghtaling
Stephen N Jones
P2860
P304
P3181
P356
10.1101/GAD.1103403
P407
P577
2003-08-15T00:00:00Z