2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death - Wikidata - wikimedia - TriplyDB

2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death

2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death

http://www.wikidata.org/entity/Q34198802

about

Brown adipose tissue and bone Caloric restriction and exercise "mimetics'': Ready for prime time?The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue.The chemical uncoupler 2,4-dinitrophenol (DNP) protects against diet-induced obesity and improves energy homeostasis in mice at thermoneutrality Toxicity of weight loss agents N-terminally glutamate-substituted analogue of gramicidin A as protonophore and selective mitochondrial uncoupler.Novel psychoactive substances of interest for psychiatry.Penetrating cations enhance uncoupling activity of anionic protonophores in mitochondria Mitochondria-targeting particles.Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue.Recent progress in the study of brown adipose tissue.A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels Evaluation of efficacy of resin hemoperfusion in patients with acute 2,4-dinitrophenol poisoning by dynamic monitoring of plasma toxin concentration.Uncoupling protein 1 of brown adipocytes, the only uncoupler: a historical perspective.Russian roulette with unlicensed fat-burner drug 2,4-dinitrophenol (DNP): evidence from a multidisciplinary study of the internet, bodybuilding supplements and DNP users.Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a systematic review Opposing tissue-specific roles of angiotensin in the pathogenesis of obesity, and implications for obesity-related hypertension Antimicrobial agent triclosan is a proton ionophore uncoupler of mitochondria in living rat and human mast cells and in primary human keratinocytes.Human adipose dynamics and metabolic health A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis The role of innate immunity in the regulation of brown and beige adipogenesis.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Mitochondria-Targeted Antioxidants and Uncouplers of Oxidative Phosphorylation in Treatment of the Systemic Inflammatory Response Syndrome (SIRS).Mitochondrial uncoupling reduces exercise capacity despite several skeletal muscle metabolic adaptations.The Gut Microbiome, Energy Homeostasis, and Implications for Hypertension.Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules.Increasing frequency of severe clinical toxicity after use of 2,4-dinitrophenol in the UK: a report from the National Poisons Information Service.Toxicokinetic Model Development for the Insensitive Munitions Component 2,4-Dinitroanisole.Beware the yellow slimming pill: fatal 2,4-dinitrophenol overdose.Metformin directly acts on mitochondria to alter cellular bioenergetics.Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss.Writing an effective review article.Heart Toxicity Related to Herbs and Dietary Supplements: Online Table of Case Reports. Part 4 of 5.A reappraisal of the proposed metabolic and antioxidant actions of butylated hydroxytoluene (BHT) in the liver.UCP1 deficiency increases adipose tissue monounsaturated fatty acid synthesis and trafficking to the liver.Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing.Wastewater-based tracing of doping use by the general population and amateur athletes.

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2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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Journal of Medical Toxicology

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2,4-dinitrophenol (DNP): a wei ...... ute toxicity and risk of death

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Johann Grundlingh

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Marwa El-Zanfaly

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Paul I Dargan

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P2860

Use of Dinitrophenol in Nutritional Disorders : A Critical Survey of Clinical Results

Mitochondrial targets of drug toxicity.

Mitochondrial uncoupling as a target for drug development for the treatment of obesity.

Dying to be thin: a dinitrophenol related fatality.

Two deaths attributed to the use of 2,4-dinitrophenol.

Deliberate poisoning with dinitrophenol (DNP): an unlicensed weight loss pill.

Dinitrophenol poisoning: a diagnosis to consider in undiagnosed fever.

Pediatric fatality following ingestion of dinitrophenol: postmortem identification of a "dietary supplement".

Extracorporeal blood purification in sepsis and sepsis-related acute kidney injury.

Dinitrophenol and obesity: an early twentieth-century regulatory dilemma.

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s13181-011-0162-6

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205-212

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10.1007/S13181-011-0162-6

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