Targeting poly(ADP-ribose) polymerase activity for cancer therapy. - Wikidata - wikimedia - TriplyDB

Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

http://www.wikidata.org/entity/Q34204660

about

Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1 Structural studies of the PARP-1 BRCT domain Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models.Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology.XAV939-mediated ARTD activity inhibition in human MB cell lines.The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3.Ovarian cancer: in search of better marker systems based on DNA repair defects Balancing repair and tolerance of DNA damage caused by alkylating agents Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-κB signaling in colorectal cancer.DNA repair in cancer: emerging targets for personalized therapy.PARP inhibitors in cancer therapy: an update.Beyond DNA repair, the immunological role of PARP-1 and its siblings.Drug treatment of cancer cell lines: a way to select for cancer stem cells?Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer.High PARP-1 expression is associated with tumor invasion and poor prognosis in gastric cancer.Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome.MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles.Poly(ADP-ribose) polymerase-3 overexpression is associated with poor prognosis in patients with breast cancer following chemotherapy Downregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer

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P2860

Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

http://www.wikidata.org/entity/Q34204660

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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type

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

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Cellular and Molecular Life Sciences

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Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

@en

P2093

Frédérique Mégnin-Chanet

http://www.w3.org/2001/XMLSchema#string

Janet Hall

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Marc A Bollet

http://www.w3.org/2001/XMLSchema#string

P2860

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

The macro domain is an ADP-ribose binding module

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif

Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

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3649-3662

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10.1007/S00018-010-0490-8

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21

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67

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2010-08-20T00:00:00Z

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2010-11-01T00:00:00Z

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mechanism of action

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