124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice
about
Molecular Imaging in Genetic MedicineUse of (64)Cu-labeled fibronectin domain with EGFR-overexpressing tumor xenograft: molecular imaging.Imaging in neurooncologyDiscovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method.Tumor imaging by means of proteolytic activation of cell-penetrating peptidesDesign and preclinical evaluation of a 99mTc-labelled diabody of mAb J591 for SPECT imaging of prostate-specific membrane antigen (PSMA).Identification of internalizing human single-chain antibodies targeting brain tumor sphere cells.Minibody-indocyanine green based activatable optical imaging probes: the role of short polyethylene glycol linkersTarget mediated disposition of T84.66, a monoclonal anti-CEA antibody: application in the detection of colorectal cancer xenograftsOptical imaging-guided cancer therapy with fluorescent nanoparticlesImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies).Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas.Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin.Radiation dose estimation using preclinical imaging with 124I-metaiodobenzylguanidine (MIBG) PET.Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging.Quantitative serial imaging of an 124I anti-CEA monoclonal antibody in tumor-bearing mice.Evaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imagingEstimation of the minimum detectable activity of preclinical PET imaging systems with an analytical method.A method of image registration for small animal, multi-modality imagingAnti-MET immunoPET for non-small cell lung cancer using novel fully human antibody fragmentsCytotoxic enhancement of a bispecific diabody by format conversion to tandem single-chain variable fragment (taFv): the case of the hEx3 diabody.Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatmentImaging and cancer: a review.Generation and characterization of a diabody targeting the αvβ6 integrin.Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging.A fully human scFv phage display library for rapid antibody fragment reformattingMonodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET.Recent trends in antibody-based oncologic imagingTargeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody FragmentRadioimaging of light chain amyloid with a fibril-reactive monoclonal antibodyAnti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-lifeRadioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges.Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokineticsAdvances in immuno-positron emission tomography: antibodies for molecular imaging in oncologyDendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry.Protein-based tumor molecular imaging probes.Engineered humanized diabodies for microPET imaging of prostate stem cell antigen-expressing tumorsImpact of expression system on the function of the C6.5 diabody PET radiotracerAntibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.
P2860
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P2860
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@ast
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@en
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@nl
type
label
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@ast
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@en
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@nl
prefLabel
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@ast
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@en
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@nl
P2093
P2860
P1476
124I-labeled engineered anti-C ...... of xenografts in athymic mice
@en
P2093
Andrew A Raubitschek
Arion F Chatziioannou
Gobalakrishnan Sundaresan
John E Shively
Lawrence E Williams
Paul J Yazaki
Ronald D Finn
Sanjiv S Gambhir
Steven M Larson
P2860
P304
P407
P577
2003-12-01T00:00:00Z