Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment - Wikidata - wikimedia - TriplyDB

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

http://www.wikidata.org/entity/Q35650818

about

Molecular Imaging of Pancreatic Cancer with Antibodies.High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells.A mutated anti-CA19-9 scFv-Fc for positron emission tomography of human pancreatic cancer xenografts.Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer.Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life IMAC capture of recombinant protein from unclarified mammalian cell feed streams Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers Biodistribution Analyses of a Near-Infrared, Fluorescently Labeled, Bispecific Monoclonal Antibody Using Optical Imaging Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor.Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer.Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors.Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery.Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers.Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore.

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

http://www.wikidata.org/entity/Q35650818

description

2011 nî lūn-bûn

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2011年論文

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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EJNMMI Research

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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

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Anna M Wu

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James S Tomlinson

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Katelyn E McCabe

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Mark D Girgis

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Tove Olafsen

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Vania Kenanova

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P2860

Cancer statistics, 2010

The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues

Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids.

Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.

124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice

Preparation of monoclonal antibodies: strategies and procedures.

Fluorophore-conjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer

Tailoring antibodies for radionuclide delivery.

Engineering of therapeutic antibodies to minimize immunogenicity and optimize function.

Antibody constructs in cancer therapy: protein engineering strategies to improve exposure in solid tumors.

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10.1186/2191-219X-1-24

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1

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1047583533

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Aizkuņģa dziedzeris

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3251041

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