High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

Item
http://www.wikidata.org/entity/Q34207491
Inducing Oncoprotein Degradation to Improve Targeted Cancer TherapyFluorescence anisotropy (polarization): from drug screening to precision medicine.Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old ageComprehensive analysis of loops at protein-protein interfaces for macrocycle design.Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions.Protein-protein interactions as drug targets.A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis.Targeting ubiquitination for cancer therapies.Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancerScreening for E3-ubiquitin ligase inhibitors: challenges and opportunities.Antitumor mechanisms when pRb and p53 are genetically inactivated.Polypharmacology of small molecules targeting the ubiquitin-proteasome and ubiquitin-like systems.Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction.Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel.
P2860

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

Item
http://www.wikidata.org/entity/Q34207491
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2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2013 թվականի ապրիլին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
@wuu
name
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@ast
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@en
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@nl
type
label
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@ast
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@en
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@nl
prefLabel
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@ast
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@en
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
High-throughput screening Alph ...... iquitin E3 ligase SCFSkp2-Cks1
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932