Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets.
about
Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channelsMechanisms of action of glucagon-like peptide 1 in the pancreasGLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependenceA novel mechanism for the suppression of a voltage-gated potassium channel by glucose-dependent insulinotropic polypeptide: protein kinase A-dependent endocytosis.Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial transcriptional complex Hap2-3-4-5Glucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytesPharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channelsGLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activationVariants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice.Regulation of insulin secretion: role of mitochondrial signalling.TRP-ing down the path to insulin secretion.An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population.The adenylyl cyclase inhibitor MDL-12,330A potentiates insulin secretion via blockade of voltage-dependent K(+) channels in pancreatic beta cellsGhrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation.Pharmacogenomics of cardiovascular complications in diabetes and obesity.Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1cRevealing the Function and the Structural Model of Ts4: Insights into the "Non-Toxic" Toxin from Tityus serrulatus VenomGluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptorsPKC and AMPK regulation of Kv1.5 potassium channelsBlockade of β-cell K(ATP) channels by the endocannabinoid, 2-arachidonoylglycerol.Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery.Glucose-sensing mechanisms in pancreatic beta-cells.A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosusInsights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets.SP6616 as a new Kv2.1 channel inhibitor efficiently promotes β-cell survival involving both PKC/Erk1/2 and CaM/PI3K/Akt signaling pathways.The MOR-1 opioid receptor regulates glucose homeostasis by modulating insulin secretion.Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells.Retinal pigment epithelial cells express a functional receptor for glucagon-like peptide-1 (GLP-1).Insulin release, peripheral insulin resistance and muscle function in protein malnutrition: a role of tricarboxylic acid cycle anaplerosis.BK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells.Signal integration at the level of ion channel and exocytotic function in pancreatic β-cells.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?Hydrogen sulfide: role in ion channel and transporter modulation in the eye.Mechanism of electromechanical coupling in voltage-gated potassium channels.Glucagon-like peptide-1: modulator of β-cell dysfunction and death.The Amino Acid Transporters of the Glutamate/GABA-Glutamine Cycle and Their Impact on Insulin and Glucagon Secretion.Reactive oxygen and nitrogen species disturb Ca(2+) oscillations in insulin-secreting MIN6 β-cells.Dynamics and modulation studies of human voltage gated Kv1.5 channel.
P2860
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P2860
Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@ast
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@en
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@nl
type
label
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@ast
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@en
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@nl
prefLabel
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@ast
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@en
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@nl
P1433
P1476
Voltage-dependent K(+) channel ...... ential as therapeutic targets.
@en
P2093
MacDonald PE
Wheeler MB
P2888
P304
P356
10.1007/S00125-003-1159-8
P577
2003-06-27T00:00:00Z
P5875
P6179
1025486356