Proflavine acts as a Rev inhibitor by targeting the high-affinity Rev binding site of the Rev responsive element of HIV-1.
about
Heterocyclic compounds that inhibit Rev-RRE function and human immunodeficiency virus type 1 replication.The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycleEffect of intercalator and Lewis acid-base branched peptide complex formation: boosting affinity towards HIV-1 RRE RNACharacterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNALong lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis.Quantum-dot-based nanosensor for RRE IIB RNA-Rev peptide interaction assay.Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization.Ligand-induced changes in 2-aminopurine fluorescence as a probe for small molecule binding to HIV-1 TAR RNATargeting folded RNA: a branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNAHIV-1 drug discovery: targeting folded RNA structures with branched peptides.Proflavine Hemisulfate as a Fluorescent Contrast Agent for Point-of-Care CytologySynthesis of HIV-1 Psi-site RNA sequences with site specific incorporation of the fluorescent base analog 2-aminopurineIdentification and Optimization of Thienopyridine Carboxamides as Inhibitors of HIV Regulatory Complexes.Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.An approach to the construction of tailor-made amphiphilic peptides that strongly and selectively bind to hairpin RNA targets.Dissecting structural transitions in the HIV-1 dimerization initiation site RNA using 2-aminopurine fluorescence.A reporter based single step assay for evaluation of inhibitors targeting HIV-1 Rev-RRE interaction.Targeting the protein-protein interactions of the HIV lifecycle.Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble.Enzymatic incorporation of emissive pyrimidine ribonucleotides.
P2860
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P2860
Proflavine acts as a Rev inhibitor by targeting the high-affinity Rev binding site of the Rev responsive element of HIV-1.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@ast
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@en
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@nl
type
label
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@ast
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@en
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@nl
prefLabel
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@ast
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@en
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@nl
P2093
P356
P1433
P1476
Proflavine acts as a Rev inhib ...... v responsive element of HIV-1.
@en
P2093
Chia-en Chang
Eric S DeJong
John P Marino
Michael K Gilson
P304
P356
10.1021/BI034252Z
P407
P577
2003-07-01T00:00:00Z