Ligand-induced changes in 2-aminopurine fluorescence as a probe for small molecule binding to HIV-1 TAR RNA
about
Discovering ligands for a microRNA precursor with peptoid microarrays.Binding of aminoglycoside antibiotics to helix 69 of 23S rRNAIdentification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.Differential analogue binding by two classes of c-di-GMP riboswitchesUsing an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs.Synthesis of HIV-1 Psi-site RNA sequences with site specific incorporation of the fluorescent base analog 2-aminopurineOligodeoxyfluorosides: Strong Sequence Dependence of Fluorescence EmissionDevelopment of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discoveryInfluence of dimethylsulfoxide on RNA structure and ligand binding.Dissecting structural transitions in the HIV-1 dimerization initiation site RNA using 2-aminopurine fluorescence.Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha.Site-specific variations in RNA folding thermodynamics visualized by 2-aminopurine fluorescence.Quadruplex formation as a molecular switch to turn on intrinsically fluorescent nucleotide analogs.Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids.Cleavage of RNA oligonucleotides by aminoglycosides.Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble.Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices.Enzymatic incorporation of emissive pyrimidine ribonucleotides.Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurineLigand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1.Fluorescence probing of T box antiterminator RNA: insights into riboswitch discernment of the tRNA discriminator base.Pyrrolo-C as a fluorescent probe for monitoring RNA secondary structure formation.Structure-activity studies on the fluorescent indicator in a displacement assay for the screening of small molecules binding to RNA.Highly emissive deoxyguanosine analogue capable of direct visualization of B-Z transition.Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription
P2860
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P2860
Ligand-induced changes in 2-aminopurine fluorescence as a probe for small molecule binding to HIV-1 TAR RNA
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@ast
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@en
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@nl
type
label
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@ast
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@en
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@nl
prefLabel
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@ast
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@en
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@nl
P2860
P356
P1433
P1476
Ligand-induced changes in 2-am ...... ecule binding to HIV-1 TAR RNA
@en
P2093
John P Marino
Thomas D Bradrick
P2860
P304
P356
10.1261/RNA.7620304
P407
P577
2004-07-23T00:00:00Z