Metastatic bone disease: role of transcription factors and future targets.
about
RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progressionThe Roles of Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Epithelial Transition (MET) in Breast Cancer Bone Metastasis: Potential Targets for Prevention and TreatmentRole of RUNX2 in Breast CarcinogenesisSIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomasA program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.MicroRNAs in the control of metastatic bone disease.hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.GPRC6A regulates prostate cancer progressionA proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genesDNA-binding small molecules as inhibitors of transcription factors.Runx2-Smad signaling impacts the progression of tumor-induced bone diseaseSubnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response.Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease.Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsivenessGenomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasionExpression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2.Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells.RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.Transcription factor networks in invasion-promoting breast carcinoma-associated fibroblasts.Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cellsMicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments.Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 RegulationThe influence of genetic ancestry and ethnicity on breast cancer survival associated with genetic variation in the TGF-β-signaling pathway: The Breast Cancer Health Disparities Study.Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancersA microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells.Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells.MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2.Molecular targets for radiation oncology in prostate cancer.The RUNX family in breast cancer: relationships with estrogen signaling.RUNX2 in mammary gland development and breast cancer.Bone tissue engineering and regenerative medicine: targeting pathological fractures.Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer.Runx3 in Immunity, Inflammation and Cancer.Runx2 and microRNA regulation in bone and cartilage diseases.
P2860
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P2860
Metastatic bone disease: role of transcription factors and future targets.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Metastatic bone disease: role of transcription factors and future targets.
@ast
Metastatic bone disease: role of transcription factors and future targets.
@en
Metastatic bone disease: role of transcription factors and future targets.
@nl
type
label
Metastatic bone disease: role of transcription factors and future targets.
@ast
Metastatic bone disease: role of transcription factors and future targets.
@en
Metastatic bone disease: role of transcription factors and future targets.
@nl
prefLabel
Metastatic bone disease: role of transcription factors and future targets.
@ast
Metastatic bone disease: role of transcription factors and future targets.
@en
Metastatic bone disease: role of transcription factors and future targets.
@nl
P2093
P2860
P1433
P1476
Metastatic bone disease: role of transcription factors and future targets.
@en
P2093
Gary S Stein
Jane B Lian
Jitesh Pratap
P2860
P356
10.1016/J.BONE.2010.05.035
P577
2010-06-01T00:00:00Z