The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
about
Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunityHuman nutrition, the gut microbiome and the immune systemmTOR Regulation of Lymphoid Cells in Immunity to PathogensMechanisms of T cell organotropismImportance of Apolipoprotein A-I in Multiple SclerosisRegulatory T Cells in Kidney Transplantation: New Directions?Kinase AKT controls innate immune cell development and functionIntegrating canonical and metabolic signalling programmes in the regulation of T cell responsesFOXO transcription factors throughout T cell biologySphingolipid signaling in metabolic disordersTreg functional stability and its responsiveness to the microenvironmentSphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyondNature and nurture in Foxp3(+) regulatory T cell development, stability, and functionImmunotherapy in autoimmune type 1 diabetesDifferential effects of rapamycin and dexamethasone in mouse models of established allergic asthmaAn approach to control relapse of inflammatory lesions after discontinuation of primary therapyHighlights of the advances in basic immunology in 2011.KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production.An update on the biology of sphingosine 1-phosphate receptors.Membranes in balance: mechanisms of sphingolipid homeostasis.Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.Sphingosine-1-phosphate and immune regulation: trafficking and beyondKinase suppressor of Ras 1 is not required for the generation of regulatory and memory T cells.Overexpression of sphingosine-1-phosphate receptor 1 and phospho-signal transducer and activator of transcription 3 is associated with poor prognosis in rituximab-treated diffuse large B-cell lymphomas.Metabolic control of regulatory T cell development and function.mTOR signaling, Tregs and immune modulation.Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.mTOR Links Environmental Signals to T Cell Fate Decisions.HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates.S1P is associated with protection in human and experimental cerebral malariaA novel role for KLF14 in T regulatory cell differentiation.Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1.The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.Lipid phosphate phosphatase 3 enables efficient thymic egress.mTOR and metabolic regulation of conventional and regulatory T cells.The molecular mechanisms of Foxp3 gene regulation.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Rapamycin attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma.Tregs and infections: on the potential value of modifying their function.
P2860
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P2860
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@ast
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@en
type
label
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@ast
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@en
prefLabel
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@ast
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
@en
P2093
P2860
P356
P1433
P1476
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells
@en
P2093
Samir Burns
Sharad Shrestha
P2860
P304
P356
10.1038/NI.1939
P407
P577
2010-09-19T00:00:00Z