The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function. - Wikidata - wikimedia - TriplyDB

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

http://www.wikidata.org/entity/Q35172754

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Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells Metabolic regulation of T cell differentiation and function T cell metabolism drives immunity IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells Modulation of T Cell Metabolism and Function through Calcium Signaling The role and regulation of mTOR in T-lymphocyte function Integrating canonical and metabolic signalling programmes in the regulation of T cell responses Metabolic reprogramming and metabolic dependency in T cells Transcriptional regulation of the NKT cell lineage Metabolic maintenance of cell asymmetry following division in activated T lymphocytes Immunometabolism of regulatory T cells Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection.p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.A critical role for the regulated wnt-myc pathway in naive T cell survival Essential role for autophagy during invariant NKT cell development.mTOR signaling, Tregs and immune modulation.Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.mTOR Links Environmental Signals to T Cell Fate Decisions.High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals.mTOR and metabolic regulation of conventional and regulatory T cells.The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.An mTORC1-Mdm2-Drosha axis for miRNA biogenesis in response to glucose- and amino acid-deprivation.TOR in the immune system.TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation.mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.A matched couple: Combining kinase inhibitors with immunotherapy for cancer treatment GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes.Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet.A critical role for Rictor in T lymphopoiesis.Regulation and function of mTOR signalling in T cell fate decisions.

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The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

http://www.wikidata.org/entity/Q35172754

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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Nature Immunology

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The tumor suppressor Tsc1 enfo ...... mune homeostasis and function.

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Geoffrey Neale

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Kai Yang

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Weifeng He

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P2860

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

mTOR: from growth signal integration to cancer, diabetes and ageing

mTOR regulates memory CD8 T-cell differentiation

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

TSC2 mediates cellular energy response to control cell growth and survival

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

Kruppel-like factor 2 regulates thymocyte and T-cell migration

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

Mitochondria and cell death: outer membrane permeabilization and beyond

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888-897

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9

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12

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Douglas R. Green

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