Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.
about
Cell-cell interactions in synovitis: antigen presenting cells and T cell interaction in rheumatoid arthritis.The evolving clinical profile of abatacept (CTLA4-Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis.Blocking costimulatory signals to induce transplantation tolerance and prevent autoimmune disease.Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles.CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis.Abatacept: a costimulatory inhibitor for treatment of rheumatoid arthritis.GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.Emerging disease modifying therapies for multiple sclerosis.CD28-independent induction of experimental autoimmune encephalomyelitis.Immunotherapies: the blockade of inhibitory signals.Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosisDistinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis.Modulating co-stimulation.Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy.Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.Regulation of experimental autoimmune encephalomyelitis with insulin-like growth factor (IGF-1) and IGF-1/IGF-binding protein-3 complex (IGF-1/IGFBP3).CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis.Opportunities for Translation from the Bench: Therapeutic Intervention of the JAK/STAT Pathway in Neuroinflammatory Diseases.Alternatives to calcineurin inhibition in renal transplantation: belatacept, the first co-stimulation blocker.Coinhibitory molecules in autoimmune diseases.B7 family checkpoint regulators in immune regulation and disease.The CD28/CTLA-4:B7 receptor system in experimental autoimmune encephalomyelitisApproaches to the treatment of central nervous system autoimmune disease using specific neuroantigen.Differential expression of B7 co-stimulatory molecules by astrocytes correlates with T cell activation and cytokine production.Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome.Increased frequency of IL-6-producing non-classical monocytes in neuromyelitis optica spectrum disorder.Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.Disease stage-dependent relationship between diffusion tensor imaging and electrophysiology of the visual system in a murine model of multiple sclerosis.Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis.Late complications of immune deviation therapy in a nonhuman primate.Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28.Differential expression of costimulatory molecules B7-1 and B7-2 on microglial cells induced by Th1 and Th2 cells in organotypic brain tissue.Expansion and preferential activation of the CD14(+)CD16(+) monocyte subset during multiple sclerosis.Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.Manipulation of costimulatory pathways in autoimmune diseasesAdenovirus-mediated gene transfer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritis
P2860
Q24805227-D449E2A1-714C-4489-9C75-F56EDB75892FQ33709339-69D6E300-6C02-4763-A5F1-E8E824475286Q33805849-A52F452D-A3ED-4727-9247-380B978D9761Q33849223-4F0A6E45-3453-4B80-B8A3-402ACE773A23Q33855058-F935E678-BE33-4450-8798-363C5B4B878FQ33939286-07AEE9D0-C905-4E39-B378-8B561A4AA29DQ34560362-548D20C6-F7D9-45EA-9DA8-1C2B929369C3Q34790295-FE934433-121F-4B02-8EFE-4C5F95C7F612Q35581158-309BA87F-8E72-4CE6-B657-64B9237B4903Q36013773-42175CF6-C2E7-41D1-907B-6C995F8260F1Q36431677-E77C0A56-350A-4911-9F97-F961695F44BFQ36542397-07CD15A2-A02C-4A32-A77D-241DDD656A8AQ36778241-79D903F3-D9BE-4510-AF43-BAE809AFB23CQ36963201-F84DE57D-44D8-4DD2-A7C9-CB5B4E565CFDQ37368148-E2739EEC-34CB-46BF-8839-B3653ED41062Q37376774-01FE3C54-348B-4F4F-A6AE-5F3BADB70623Q37381231-71365CCA-F9F8-40EF-B4CF-24912CF5568BQ37579811-FCEECB76-953E-475E-B637-4575BC00F4C9Q37670027-BBEBF41B-F2F9-49B7-ABE6-19A8AD67F0C0Q37793216-9FA07E8C-6E31-4577-B2F2-23110E620157Q38045307-4435F6CD-5A2F-4503-9627-F6F7B98ACD47Q38129635-AC1E687F-4C1C-4C9B-A247-AC1366E2AC44Q40343843-6F44BF9B-2D18-40A6-940E-EF1F90ABDF23Q40862395-72E4DA1D-0B1E-4D95-8594-DF43AB524999Q40945547-861BC52A-5854-41BE-BF66-BDE9940E7569Q40972080-3FDD4767-8782-435C-9C32-CD589F63C622Q41962690-8582DE92-0193-47F7-8CB9-1AB4C4C96206Q42006087-55B1E670-538B-4388-8F91-769DD295E05BQ44501597-6E6E039F-6F98-46AB-B85D-601DA43CB541Q45890414-35CFA4DF-C92B-4959-92AC-06A55EA817FEQ46594595-5C9740B7-1274-47C6-8DB5-5858805D9DAAQ48751155-FB0F5B93-C0E9-4752-A950-20ABDEAC128DQ52960346-DA828867-24BA-49DA-A266-57EA244CFD6BQ53099338-6B18451C-B534-423E-A881-4546E4A48BE2Q53407459-31E467B6-A051-4059-A2A9-33A6119049DCQ56904986-9C884560-B4F6-45D4-AD78-4047BB314F5AQ56905891-55BE1DFD-5C56-4872-950D-DB2807DFE446
P2860
Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Long-term inhibition of murine ...... y role for CD28 costimulation.
@ast
Long-term inhibition of murine ...... y role for CD28 costimulation.
@en
Long-term inhibition of murine ...... y role for CD28 costimulation.
@nl
type
label
Long-term inhibition of murine ...... y role for CD28 costimulation.
@ast
Long-term inhibition of murine ...... y role for CD28 costimulation.
@en
Long-term inhibition of murine ...... y role for CD28 costimulation.
@nl
prefLabel
Long-term inhibition of murine ...... y role for CD28 costimulation.
@ast
Long-term inhibition of murine ...... y role for CD28 costimulation.
@en
Long-term inhibition of murine ...... y role for CD28 costimulation.
@nl
P2093
P2860
P356
P1476
Long-term inhibition of murine ...... ey role for CD28 costimulation
@en
P2093
J L Trotter
K S Giacoletto
R M Keeling
T J Girard
P2860
P304
P356
10.1172/JCI117982
P407
P577
1995-06-01T00:00:00Z