GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. - Wikidata - wikimedia - TriplyDB

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

http://www.wikidata.org/entity/Q34790295

about

Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis Targeting Homeostatic T Cell Proliferation to Control Beta-Cell Autoimmunity Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease Potassium channels, memory T cells, and multiple sclerosis Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker Recurrence of autoimmunity following pancreas transplantation.Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease.HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease The role of the thymus in tolerance.Proliferation assay amplification by IL-2 in model primary and recall antigen systems.Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis.ZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adults Controlling the controls: GAD65 autoreactive T cells in type 1 diabetes.Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.Tolerogenic vaccination reduced effector memory CD4 T cells and induced effector memory Treg cells for type I diabetes treatment Loureirin B, an essential component of Sanguis Draxonis, inhibits Kv1.3 channel and suppresses cytokine release from Jurkat T cells CD28 costimulation independence of target organ versus circulating memory antigen-specific CD4+ T cells N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.Effect of FTY720 on some physiological indexes of Non-Obese Diabetic (NOD) Mice.Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases Allelic variant in CTLA4 alters T cell phosphorylation patterns Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes.Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters.Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation.Molecular mechanisms of HLA association with autoimmune diseases.Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus.Voltage-gated potassium channels as therapeutic targets.Detection of GAD65 autoreactive T-cells by HLA class I tetramers in type 1 diabetic patients.Autoimmunity risk alleles in costimulation pathways.Kv1.3 potassium channels as a therapeutic target in multiple sclerosis.Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.Genetic Susceptibility to Multiple Sclerosis: The Role of FOXP3 Gene Polymorphism.The potential of multimer technologies in type 1 diabetes prediction strategies.

P2860

Q24657847-9B4C60EA-29B0-47D6-B807-C551681C6D90 Q24675746-4228FC12-358B-4591-8E19-C2CC716BB042 Q24676659-591D5611-57F6-4F1E-8664-C5B33889D937 Q24685784-3B094146-81B2-4D35-ADDD-9F13C258064F Q26764999-4D118F45-CC1B-45BA-84E0-6478F225C36E Q28252713-931E2B40-B434-44B5-B7D3-971F14C99220 Q28281365-4A5D03A5-BE48-46BB-AF71-B4F1DE7863A1 Q28303760-7221B0CA-24C1-46CF-87F5-8EC30E4883CA Q28482737-9852B625-4C48-439E-8791-74E3D2A48331 Q33599426-D1A86D1B-1A8A-4A85-8CCA-FB65FB40D87B Q33768325-9512590F-FA56-4038-9A09-43B70EDF4E02 Q33892217-AF505DE1-C4A3-4B23-BC46-DB54C4DBA2A3 Q33998193-D4396AAD-9ED1-45CD-A200-0974F03C2771 Q34103905-BAAAED28-2340-4F7A-85BF-E1E1764057BD Q34309984-059116AB-93D8-45A6-8B41-A799B73117C7 Q34311395-5BADD781-B0D4-41F3-9D90-C1D8B308DFE5 Q34580119-19C8A988-721C-4980-AB97-B413B8CD4603 Q34584056-5C52C2BF-B20B-414E-8A45-200F69CC455A Q34746164-7171146C-647B-432B-B8E0-390DCAF9450C Q34875345-FBA12400-22AD-4F81-9A3F-2F9784202382 Q35563291-3C573D05-06F8-4AFF-91A0-861F248998CF Q35679137-4C6F2404-E5C8-4825-96A7-AF6EEBE8F403 Q35756367-E2CD56E7-9291-4991-9342-6FEEECCBBBB2 Q36057311-F4F2FC5C-DC9A-4F54-9442-B8020C51EDA8 Q36097325-74B52A0F-3494-48D9-A5DB-CAAC5705E9F4 Q36276908-D41D7E50-652B-424C-839F-E0332F73DA72 Q36310443-8B8BC4AD-B970-4004-86B9-0CD2585AA800 Q36330011-D608A8B5-E561-4794-B18C-0E419F45E126 Q36399006-27A532F1-B736-4A35-8B51-2BD750E1526A Q36865485-F0ADF287-AEA9-468B-A3CF-914C89DDA19F Q37328601-297B7A79-1F69-4559-A6AC-B5A7CD574FCA Q37346963-CE35C697-DE54-49CD-B9A5-30ED154E8892 Q37424283-3AE854F0-647F-4A7B-9581-82C4BCF991B4 Q37464784-DDBC342D-8FE4-492E-8897-5AE1A7E93DF7 Q37474056-3EDD95E2-DBEB-43DC-A910-4A4DD6C81142 Q37474977-DD1BD5DC-3A7C-4141-9330-29BD3F13CFF0 Q37523986-6A7FD3D1-0F98-43AD-A68C-998760A33D43 Q37599880-C9F4871B-4B50-4025-84B9-C1FDB6B32AF8 Q37725869-408C931D-8EA1-429A-940E-AB820B43AEF5 Q37838895-A43EDAEB-0760-4521-9753-E8AB2CB2E730

P2860

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

http://www.wikidata.org/entity/Q34790295

description

2002 nî lūn-bûn

@nan

2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@ast

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@en

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@nl

type

label

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@ast

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@en

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@nl

prefLabel

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@ast

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@en

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@nl

P1433

Q34790295-9A1C0B37-27FF-40B4-BF6F-DF6A5E372196

P1476

Q34790295-81087099-659E-4565-9BB4-550157F4EF46

P2093

Q34790295-B8C52F9D-3E62-47F0-955A-15B4043230A7

Q34790295-C3C8EB28-6644-4BA2-91C1-31C7542B1A1F

Q34790295-DB403418-272F-45E8-A7D5-A6B7518E7991

P2860

Q34790295-0CC9FC27-E4B1-46DE-813B-36064C82557F

Q34790295-15857F92-5330-4F84-B996-91BB37C00147

Q34790295-163C3E72-8AA3-44B7-AF59-0DE80B801EFC

Q34790295-197FA9C4-B607-4827-AE76-ABBA48F5784D

Q34790295-1C6F88B3-BC1A-4943-ADE0-6F459D5C127A

Q34790295-29B02CF8-CD61-4F1C-9383-514EA6FD1F57

Q34790295-2B8A3AF6-125C-4BB7-BA81-16321E2E11F3

Q34790295-2F50D80D-1283-49B1-9472-D105EFEE07EE

Q34790295-38253CE1-2671-4D99-AB15-2E9FD265E801

Q34790295-3FD226EE-FD93-40FC-BC51-BE27F6DACBC9

P304

Q34790295-93EA34EF-6A5A-4201-8EB1-BB03A3CCAC25

P31

Q34790295-DE6CE225-80D6-4C39-B347-68CF73751B7D

P356

Q34790295-AA69B351-263C-411D-B635-06E4AFAB06E9

P407

Q34790295-E578C8A1-32E6-4532-958F-B02101E76B04

P433

Q34790295-2157DAED-56D7-4F34-87E7-AD4633A9C332

P478

Q34790295-56B52337-36E3-4310-92A6-93B8A1DDE254

P50

Q34790295-C6A9AA9D-04CF-4140-91CA-777BD5D02EE4

P577

Q34790295-1ADC437A-A050-4061-8F2F-21317399E3BE

P698

Q34790295-0090FF62-B48A-402F-96F9-D7763C8EFA32

P921

Q34790295-66F59B85-B8D3-4597-AE36-434338C63BF9

P932

Q34790295-77093F0E-3D2A-4591-BEAA-D9248B92F36D

P356

P1433

Journal of Clinical Investigation

P1476

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.

@en

P2093

Sally C Kent

http://www.w3.org/2001/XMLSchema#string

Tihamer Orban

http://www.w3.org/2001/XMLSchema#string

Vissia Viglietta

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

CTLA-4 can function as a negative regulator of T cell activation

The role of the CD28 receptor during T cell responses to antigen

A new member of the immunoglobulin superfamily--CTLA-4

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

Type I diabetes mellitus. A chronic autoimmune disease.

Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.

P304

895-903

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI0214114

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

109

http://www.w3.org/2001/XMLSchema#string

P50

David A. Hafler

P577

2002-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11927616

http://www.w3.org/2001/XMLSchema#string

P921

P932

150925

http://www.w3.org/2001/XMLSchema#string