Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice
about
The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer's disease phenotypeAmyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids.Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's DiseaseGlucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse modelHomocysteine modulates 5-lipoxygenase expression level via DNA methylation.Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase.A COX/5-LOX Inhibitor Licofelone Revealed Anticonvulsant Properties Through iNOS Diminution in Mice.Dissecting the Role of 5-Lipoxygenase in the Homocysteine-Induced Alzheimer's Disease Pathology.The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy.Overexpression of 5-Lipoxygenase Worsens the Phenotype of a Mouse Model of Tauopathy.Brain 5-lipoxygenase over-expression worsens memory, synaptic integrity, and tau pathology in the P301S mice.Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology.Selenomethionine reduces the deposition of beta-amyloid plaques by modulating β-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease.Neuropsychiatric Events Associated with Leukotriene-Modifying Agents: A Systematic Review.Antileukotriene therapy by reducing tau phosphorylation improves synaptic integrity and cognition of P301S transgenic mice.
P2860
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P2860
Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@ast
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@en
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@nl
type
label
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@ast
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@en
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@nl
prefLabel
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@ast
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@en
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@nl
P2093
P2860
P1476
Zileuton restores memory impai ...... aged Alzheimer's disease mice
@en
P2093
Alana N Vagnozzi
Antonio Di Meco
Domenico Praticò
Elisabetta Lauretti
P2860
P304
P356
10.1016/J.NEUROBIOLAGING.2014.05.016
P577
2014-05-27T00:00:00Z