5-Lipoxygenase: regulation of expression and enzyme activity.
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Genetic variants in TNFa, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthmaAnalysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MSIndirubin-3'-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migrationEsterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infectionEnhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acidInhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilonTime-Course Study of the Transcriptome of Peripheral Blood Mononuclear Cells (PBMCs) from Sheep Infected with Fasciola hepaticaMammalian lipoxygenases and their biological relevanceBiosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acidSurvival regulation of leukemia stem cells5-lipoxygenase mRNA and protein isoformsThe eosinophil chemoattractant 5-oxo-ETE and the OXE receptorInvolvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: in vitro and in vivo evidenceA novel neurotrophic drug for cognitive enhancement and Alzheimer's diseasePro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in InflammationGene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease.Evidence for an ionic intermediate in the transformation of fatty acid hydroperoxide by a catalase-related allene oxide synthase from the Cyanobacterium Acaryochloris marina5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice.Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.5-Lipoxygenase in mouse cerebellar Purkinje cellsNatural forms of vitamin E and 13'-carboxychromanol, a long-chain vitamin E metabolite, inhibit leukotriene generation from stimulated neutrophils by blocking calcium influx and suppressing 5-lipoxygenase activity, respectively.Formation of a cyclopropyl epoxide via a leukotriene A synthase-related pathway in an anaerobic reaction of soybean lipoxygenase-1 with 15S-hydroperoxyeicosatetraenoic acid: evidence that oxygen access is a determinant of secondary reactions with faVery long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy.Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids.Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay12-lipoxygenase: a potential target for novel anti-platelet therapeutics.Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease miceSuppression of oxidative stress and 5-lipoxygenase activation by edaravone improves depressive-like behavior after concussion.Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligandsResolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarctionRegulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach.Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family membersMicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits.Claude H. Organ, Jr. memorial lecture: splanchnic hypoperfusion provokes acute lung injury via a 5-lipoxygenase-dependent mechanism.Mitogen-activated protein kinase phosphatase-1 deficiency decreases atherosclerosis in apolipoprotein E null mice by reducing monocyte chemoattractant protein-1 levels.5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo.
P2860
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P2860
5-Lipoxygenase: regulation of expression and enzyme activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
5-Lipoxygenase: regulation of expression and enzyme activity.
@en
type
label
5-Lipoxygenase: regulation of expression and enzyme activity.
@en
prefLabel
5-Lipoxygenase: regulation of expression and enzyme activity.
@en
P50
P1476
5-Lipoxygenase: regulation of expression and enzyme activity.
@en
P2093
Bengt Samuelsson
P304
P356
10.1016/J.TIBS.2007.06.002
P577
2007-06-18T00:00:00Z