Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion. - Wikidata - wikimedia - TriplyDB

Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.

Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.

http://www.wikidata.org/entity/Q34231901

about

Adiponectin signaling and function in insulin target tissues Peroxisome proliferator activated receptors at the crossroad of obesity, diabetes, and pancreatic cancer Pancreatic regulation of glucose homeostasis Skeletal muscle as a therapeutic target for delaying type 1 diabetic complications Potential roles of GPR120 and its agonists in the management of diabetes Adiponectin, driver or passenger on the road to insulin sensitivity?Islet inflammation: a unifying target for diabetes treatment?Growth Hormone-Releasing Hormone in Diabetes Obesity-Related Digestive Diseases and Their Pathophysiology Adiponectin: an attractive marker for metabolic disorders in Chronic Obstructive Pulmonary Disease (COPD)Obesity, inflammation, and lung injury (OILI): the good.Maternal high folic acid supplement promotes glucose intolerance and insulin resistance in male mouse offspring fed a high-fat diet.New insight into adiponectin role in obesity and obesity-related diseases.Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling.Development of second generation peptides modulating cellular adiponectin receptor responses.Beneficial metabolic effects of CB1R anti-sense oligonucleotide treatment in diet-induced obese AKR/J mice.High glucose predisposes gene expression and ERK phosphorylation to apoptosis and impaired glucose-stimulated insulin secretion via the cytoskeleton Globular adiponectin protects H9c2 cells from palmitate-induced apoptosis via Akt and ERK1/2 signaling pathways.A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetes Adiponectin regulates vascular endothelial growth factor-C expression in macrophages via Syk-ERK pathway.Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle Drosophila adiponectin receptor in insulin producing cells regulates glucose and lipid metabolism by controlling insulin secretion.Effects of ferulic acid and γ-oryzanol on high-fat and high-fructose diet-induced metabolic syndrome in rats.A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells.miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets.Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial.Potential mechanisms of exercise in gestational diabetes Adipocytes under assault: environmental disruption of adipose physiology.Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose Adipokines and insulin action: A sensitive issue.Adiponectin: mechanistic insights and clinical implications.Mesenchymal stem cell therapy in diabetes mellitus: progress and challenges The role of adiponectin signaling in metabolic syndrome and cancer.Leptin and adiponectin: emerging therapeutic targets in breast cancer.Diabetes and beta cell function: from mechanisms to evaluation and clinical implications.High-density lipoprotein, beta cells, and diabetes .Pathogenesis and management of the diabetogenic effect of statins: a role for adiponectin and coenzyme Q10?Bariatric surgery: beta cells in type 2 diabetes remission.

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Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.

http://www.wikidata.org/entity/Q34231901

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

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2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Adiponectin-induced ERK and Ak ...... gene expression and secretion.

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Adiponectin-induced ERK and Ak ...... gene expression and secretion.

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Adiponectin-induced ERK and Ak ...... gene expression and secretion.

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type

label

Adiponectin-induced ERK and Ak ...... gene expression and secretion.

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Adiponectin-induced ERK and Ak ...... gene expression and secretion.

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Adiponectin-induced ERK and Ak ...... gene expression and secretion.

@nl

prefLabel

Adiponectin-induced ERK and Ak ...... gene expression and secretion.

@ast

Adiponectin-induced ERK and Ak ...... gene expression and secretion.

@en

Adiponectin-induced ERK and Ak ...... gene expression and secretion.

@nl

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JBC.M109.085084

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Journal of Biological Chemistry

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Adiponectin-induced ERK and Ak ...... gene expression and secretion.

@en

P2093

Aamir Suhail

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Alpana Bhattacharjee

http://www.w3.org/2001/XMLSchema#string

Gary Sweeney

http://www.w3.org/2001/XMLSchema#string

Mansa Krishnamurthy

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Nadeeja Wijesekara

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P2860

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Disruption of IRS-2 causes type 2 diabetes in mice

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

Disruption of adiponectin causes insulin resistance and neointimal formation

A novel serum protein similar to C1q, produced exclusively in adipocytes

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

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33623-33631

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44

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285

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Michael B. Wheeler

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2010-08-13T00:00:00Z

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20709750

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phosphorylation

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2962460

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