PAFc, a key player in MLL-rearranged leukemogenesis. - Wikidata - wikimedia - TriplyDB

PAFc, a key player in MLL-rearranged leukemogenesis.

PAFc, a key player in MLL-rearranged leukemogenesis.

http://www.wikidata.org/entity/Q34245737

about

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders.Disordered epigenetic regulation in MLL-related leukemia.Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.The Roles of the Paf1 Complex and Associated Histone Modifications in Regulating Gene Expression EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells Systematic identification of Ctr9 regulome in ERα-positive breast cancer Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.SIAH proteins: critical roles in leukemogenesis.

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P2860

PAFc, a key player in MLL-rearranged leukemogenesis.

http://www.wikidata.org/entity/Q34245737

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

PAFc, a key player in MLL-rearranged leukemogenesis.

@ast

PAFc, a key player in MLL-rearranged leukemogenesis.

@en

PAFc, a key player in MLL-rearranged leukemogenesis.

@nl

type

label

PAFc, a key player in MLL-rearranged leukemogenesis.

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PAFc, a key player in MLL-rearranged leukemogenesis.

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PAFc, a key player in MLL-rearranged leukemogenesis.

@nl

prefLabel

PAFc, a key player in MLL-rearranged leukemogenesis.

@ast

PAFc, a key player in MLL-rearranged leukemogenesis.

@en

PAFc, a key player in MLL-rearranged leukemogenesis.

@nl

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PAFc, a key player in MLL-rearranged leukemogenesis.

@en

P2093

Andrew G Muntean

http://www.w3.org/2001/XMLSchema#string

Jay L Hess

http://www.w3.org/2001/XMLSchema#string

Jiaying Tan

http://www.w3.org/2001/XMLSchema#string

P2860

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS

The human PAF complex coordinates transcription with events downstream of RNA synthesis.

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.

The parafibromin tumor suppressor protein is part of a human Paf1 complex

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.

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461-465

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scholarly article

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10.18632/ONCOTARGET.181

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6

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1

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2010-10-01T00:00:00Z

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47636629

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21037944

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2965052

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