An optimized two-finger archive for ZFN-mediated gene targeting. - Wikidata - wikimedia - TriplyDB

An optimized two-finger archive for ZFN-mediated gene targeting.

An optimized two-finger archive for ZFN-mediated gene targeting.

http://www.wikidata.org/entity/Q34250428

about

Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleases Genome-editing Technologies for Gene and Cell Therapy Genetic spell-checking: gene editing using single-stranded DNA oligonucleotides Enabling functional genomics with genome engineering Designed nucleases for targeted genome editing The application of genome editing in studying hearing loss Mutagenesis and phenotyping resources in zebrafish for studying development and human disease ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering CRISPR-Cas systems for editing, regulating and targeting genomes Next-generation mammalian genetics toward organism-level systems biology Light-inducible gene regulation with engineered zinc finger proteins Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.The functional significance of common polymorphisms in zinc finger transcription factors Chimeric TALE recombinases with programmable DNA sequence specificity Highly active zinc-finger nucleases by extended modular assembly A library of TAL effector nucleases spanning the human genome.Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.Simultaneous screening and validation of effective zinc finger nucleases in yeast Heritable and precise zebrafish genome editing using a CRISPR-Cas system Deep sequencing of large library selections allows computational discovery of diverse sets of zinc fingers that bind common targets.Understanding DNA-binding specificity by bacteria hybrid selection.A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing.Poly peak parser: Method and software for identification of unknown indels using sanger sequencing of polymerase chain reaction products DNA-binding-domain fusions enhance the targeting range and precision of Cas9.Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineering Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases.A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly.Targeted chromosomal deletions and inversions in zebrafish.Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells.A new strategy for gene targeting and functional proteomics using the DT40 cell line.NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish.Bacterial cellular engineering by genome editing and gene silencing Evaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases.An improved predictive recognition model for Cys(2)-His(2) zinc finger proteins.Fatty Acid Binding Protein 11a Is Required for Brain Vessel Integrity in Zebrafish Advances in targeted genome editing.

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An optimized two-finger archive for ZFN-mediated gene targeting.

http://www.wikidata.org/entity/Q34250428

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

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type

label

An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

@en

An optimized two-finger archive for ZFN-mediated gene targeting.

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prefLabel

An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

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An optimized two-finger archive for ZFN-mediated gene targeting.

@en

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Abirami Lakshmanan

http://www.w3.org/2001/XMLSchema#string

Amy L Rayla

http://www.w3.org/2001/XMLSchema#string

Ankit Gupta

http://www.w3.org/2001/XMLSchema#string

Gary D Stormo

http://www.w3.org/2001/XMLSchema#string

Ryan G Christensen

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Scot A Wolfe

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P2860

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

WebLogo: A Sequence Logo Generator

Unexpected failure rates for modular assembly of engineered zinc fingers

Genome editing with engineered zinc finger nucleases

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10.1038/NMETH.1994

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