Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination - Wikidata - wikimedia - TriplyDB

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

http://www.wikidata.org/entity/Q34253257

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miRNAs As Emerging Regulators of Oligodendrocyte Development and Differentiation Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury The polarity protein Scribble regulates myelination and remyelination in the central nervous system Kif14 mutation causes severe brain malformation and hypomyelination Targeted ablation of oligodendrocytes triggers axonal damage MicroRNA-23a promotes myelination in the central nervous system Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis.Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation.Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease.Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age.Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS Lipidome and proteome map of myelin membranes.Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS.Continuous and low-energy 125I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth.Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.The thrombin receptor is a critical extracellular switch controlling myelination.Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brain Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.Glia Disease and Repair-Remyelination Axonal thinning and extensive remyelination without chronic demyelination in spinal injured rats.Apcdd1 stimulates oligodendrocyte differentiation after white matter injury.Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination.Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation.Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion.Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling.ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function.Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system.Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration.PIKE is essential for oligodendroglia development and CNS myelination.The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon.

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Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

http://www.wikidata.org/entity/Q34253257

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@ast

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@en

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@nl

type

label

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@ast

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@en

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@nl

prefLabel

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@ast

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@en

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@nl

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P1433

Annals of Neurology

P1476

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

@en

P2093

Chao Zhao

http://www.w3.org/2001/XMLSchema#string

Emily P Harrington

http://www.w3.org/2001/XMLSchema#string

Sovann Kaing

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Stephen P J Fancy

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P2860

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Type III neuregulin-1 promotes oligodendrocyte myelination

Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

Axonal neuregulin-1 regulates myelin sheath thickness

Late-onset neurodegeneration in mice with increased dosage of the proteolipid protein gene

Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation

Neuregulin-1 type III determines the ensheathment fate of axons

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

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703-716

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scholarly article

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10.1002/ANA.22090

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5

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68

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David H Rowitch

Robin J.M. Franklin

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2010-11-01T00:00:00Z

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46307629

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20853437

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oligodendrocyte

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2966537

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