Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
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miRNAs As Emerging Regulators of Oligodendrocyte Development and DifferentiationBalancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderSystemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injuryThe polarity protein Scribble regulates myelination and remyelination in the central nervous systemKif14 mutation causes severe brain malformation and hypomyelinationTargeted ablation of oligodendrocytes triggers axonal damageMicroRNA-23a promotes myelination in the central nervous systemEstrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis.Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligandGermline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation.Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease.Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age.Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNSLipidome and proteome map of myelin membranes.Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS.Continuous and low-energy 125I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth.Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extentAxin2 as regulatory and therapeutic target in newborn brain injury and remyelination.The thrombin receptor is a critical extracellular switch controlling myelination.Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brainErk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.Glia Disease and Repair-RemyelinationAxonal thinning and extensive remyelination without chronic demyelination in spinal injured rats.Apcdd1 stimulates oligodendrocyte differentiation after white matter injury.Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination.Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation.Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion.Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling.ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function.Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system.Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration.PIKE is essential for oligodendroglia development and CNS myelination.The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon.
P2860
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P2860
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@ast
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@en
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@nl
type
label
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@ast
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@en
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@nl
prefLabel
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@ast
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@en
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@nl
P2093
P2860
P356
P1433
P1476
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
@en
P2093
Emily P Harrington
Sovann Kaing
Stephen P J Fancy
P2860
P304
P356
10.1002/ANA.22090
P577
2010-11-01T00:00:00Z